[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549320":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":35,"responsibleParty":58,"collaborators":60,"id":63,"slug":19,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":19,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":19,"enrollmentInfo":71,"targetDuration":19,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":83,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Royal North Shore Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Gynaecological HDR brachytherapy patients","EXPERIMENTAL","Using 3D-printed custom applicators to treat gynaecological HDR brachytherapy patients",[13],"Device: 3D-printed custom applicator",[15],{"type":16,"name":17,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","3D-printed custom applicator",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Marita Morgia, MD","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":5,"role":26},"Jeremy Booth, PhD QMP","STUDY_DIRECTOR",[28,32],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},"CONTACT","9463 1300","Marita.Morgia@health.nsw.gov.au",{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},"94631300","jeremy.booth@health.nsw.gov.au",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","St Leonards","New South Wales","2067","Australia","AU",{"type":44,"coordinates":45},"Point",[46,47],151.19836,-33.82344,{"lat":47,"lon":46},[50,54],{"name":51,"role":29,"phone":52,"phoneExt":19,"email":53},"Carol Kwong","02 9463 1339","Carolyn.Kwong@health.nsw.gov.au",{"name":55,"role":29,"phone":56,"phoneExt":19,"email":57},"Heidi Tsang","02 9463 1340","Heidi.Tsang@health.nsw.gov.au",{"type":59,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[61],{"name":62,"class":6},"Northern Sydney and Central Coast Area Health Service","100549320",false,"NCT06432478","3D Printed Custom Applicators for HDR BT (DISCO)","Study of 3D-printed Custom Applicators for Intracavitary HDR Gynaecological Brachytherapy (DISCO)","Inclusion Criteria:\n\n* Able to give informed consent\n* Patients indicated for intracavitary brachytherapy\n* FIGO stage I-IVA\n* ECOG 0-2\n* Primary endometrial cancer, primary vaginal cancer, primary vulva cancer, recurrent gynaecological cancer\n\nExclusion Criteria:\n\n* Pregnancy\n* Patients contraindicated for brachytherapy\n* Inflammatory bowel disease\u002Fhistory of adhesions\u002Fbowel obstruction\n* Renal transplant\u002Fhorseshoe kidney\n* Patients with significant LVSI or pelvic sidewall invasion\n* Patients requiring interstitial brachytherapy implants","FEMALE","18 Years",{"count":72,"type":73},10,"ESTIMATED","INTERVENTIONAL",[76],"NA","Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. This study is a Phase IIa non-randomised interventional pilot trial that will investigate the feasibility of successfully treating patients with 3D-printed custom applicators.",[79,80,81,82],"Gynecologic Cancer","Endometrial Cancer","Vaginal Cancer","Vulva Cancer",[84,85,86],"3D-printed applicator","Gynaecological Cancer","Brachytherapy","2026-02-04",{"date":89,"type":90},"2026-02-06","ACTUAL",{"date":92,"type":90},"2023-11-24",{"date":94,"type":73},"2028-09",{"name":5,"class":6},1]