[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525193":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":28,"centralContacts":29,"locations":39,"responsibleParty":58,"collaborators":28,"id":61,"slug":28,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":28,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":28,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":42,"whyStopped":28,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR","The control group (CG) irrigated in the standard FDA consumer-recommended position, defined as leaning forward with a natural ear-to-shoulder head tilt.",[13],"Other: Irrigation head position",{"label":15,"type":16,"description":17,"interventionNames":18},"Backfill group","EXPERIMENTAL","Backfill group (BG) subjects irrigated with a head tilt of 90 degrees ear-to-shoulder and used the nostril closest to the ground.",[13],{"label":20,"type":16,"description":21,"interventionNames":22},"Model group","Finally, the model group (MG) irrigated in an optimal position based on their 3D nasal replica. This patient-specific position was communicated to each MG patient with clear instructions during an in-person training session.",[13],[24],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"Irrigation head position","Patients irrigated their sinuses with once daily 2 mg mometasone using 240 mL NeilMed sinus rinse bottles for 8 weeks. The only factor that varied between groups was the head position patients irrigated in.",[15,9,20],null,[30,35],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Kai Zhao, PhD","CONTACT","2673032322","zhao.1949@osu.edu",{"name":36,"role":32,"phone":37,"phoneExt":28,"email":38},"Zachary T. Root, BS","6145609257","zachary.root@osumc.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"The Ohio State University Eye and Ear Institue","RECRUITING","Columbus","Ohio","43212","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-82.99879,39.96118,{"lat":52,"lon":51},[55,56],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},{"name":31,"role":57,"phone":28,"phoneExt":28,"email":28},"PRINCIPAL_INVESTIGATOR",{"type":57,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Kai Zhao","Associate Professor","100525193",false,"NCT06118554","3D Printing to Improve Nasal Irrigation Outcome","3D Printing for Topical Nasal Corticosteroid Irrigations: a Randomized Clinical Trial.","Inclusion Criteria:\n\n* Chronic rhinosinusitis without nasal polyps (CRSsNP) or Chronic rhinosinusitis with nasal polyps (CRSwNP).\n\nExclusion Criteria:\n\n* Patients with significant nasal polyps (as determined by a clinician) were excluded upfront due to the unlikeness of irrigation penetration regardless of the head position. Patients with significant atopy, cystic fibrosis, granulomatosis with polyangiitis or other connective tissue disorder, and current pregnancy were also excluded.","ALL","18 Years","75 Years",{"count":71,"type":72},200,"ESTIMATED","INTERVENTIONAL",[75],"NA","Three-dimensional (3D) printing has been an emerging technology with uses in a wide array of fields. This research aims to use 3D printing as a tool to provide personalized education to maximize treatment efficacy based on the patient's individual anatomy. With increased irrigation to the sinuses, we hypothesize there will be improved patient satisfaction and higher quality of life. The outcomes of this research could lead to a new option for patients who live with chronic rhinosinusitis are not candidates for surgery or are interested in less invasive options. The 3D printed nasal replica is not something that would be implanted, rather it is a hand-held device used specifically for participants to better understand their nasal anatomy.",[78,79],"Chronic Rhinosinusitis With Nasal Polyps","Chronic Rhinosinusitis Without Nasal Polyps",[81],"3D modeling","2026-05-21",{"date":84,"type":85},"2026-05-26","ACTUAL",{"date":87,"type":85},"2021-11-01",{"date":89,"type":72},"2027-12-30",{"name":5,"class":6},1]