A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-95
SponsorUniversity of Florida
About this trial
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy control
Eligibility criteria
Qualifiers
Age 60-95 years
Montreal Cognitive Assessment (MoCA) score 18 and above (scores will be adjusted for education)
Able to receive electrical stimulation
Ability to comprehend conversational voices
Disqualifiers
Failure to provide informed consent
Contraindications to MRI recording (e.g., any kind of ferrous metallic stents or ferrous metal objects in the body, heart valve prosthesis, or other metal implants, claustrophobia, neurostimulation system, defibrillator, pacemaker, or other implanted device)
Left-handed, or left hand dominant
History of neurological, seizures, and psychiatric disorders, traumatic brain injury, incidence of stroke involving large vessel
Trial design
Treatments tested in this trial
- Active tDCS
- Sham tDCS
Treatment groups
110 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Florida
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov