[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575063":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":24,"centralContacts":34,"locations":40,"responsibleParty":94,"collaborators":24,"id":99,"slug":24,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":106,"sex":107,"minAge":108,"maxAge":24,"enrollmentInfo":109,"targetDuration":24,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"University of Bari","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Multidomain group","EXPERIMENTAL","Participants who undergo regularly a series of activities involving different domains (e.g., physical activity, choir, horticulture etc.).",[13],"Other: Multidomain Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Active control group","ACTIVE_COMPARATOR","Participants who undergo regularly a series of activities but not musical acivities",[19],"Other: General activities",{"label":21,"type":22,"description":23,"interventionNames":24},"Passive control group","NO_INTERVENTION","Participants who undergo any activity or just sporadic activities",null,[26,30],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":24},"Multidomain Intervention","The intervention is distinguished by its multidomain approach combining cognitive, social, and musical activities through choir participation, targeting holistic cognitive and emotional benefits, unlike active controls (general activities) and passive controls (no activities).",[9],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":24},"General activities","Participants will carry out a series of physical, manual and\u002For intellectual activities (e.g., horticulture, physical activities, theatre, learning programs etc.) but not musical activities",[15],[35],{"name":36,"role":37,"phone":38,"phoneExt":24,"email":39},"Elvira Brattico, Professor","CONTACT","+390805714702","elvira.brattico@uniba.it",[41,60,72,83],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Musica In Gioco","RECRUITING","Adelfia","Bari","70010","Italy","IT",{"type":50,"coordinates":51},"Point",[52,53],16.87208,41.0033,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":58,"phoneExt":24,"email":59},"Andrea Gargiulo, Prof.","+393381931953","MusicaInGioco@gmail.com",{"facility":5,"status":43,"city":45,"state":45,"zip":61,"country":47,"countryCode":48,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"70121",{"type":50,"coordinates":63},[64,65],16.86982,41.12066,{"lat":65,"lon":64},[68],{"name":69,"role":37,"phone":70,"phoneExt":24,"email":71},"Mariangela Lippolis","+393284154560","mariangela.lippolis@uniba.it",{"facility":73,"status":43,"city":45,"state":45,"zip":74,"country":47,"countryCode":48,"cosmosGeoPoint":75,"geoPoint":77,"contacts":78},"Centro Servizi per la famiglia Libertà","70122",{"type":50,"coordinates":76},[64,65],{"lat":65,"lon":64},[79],{"name":80,"role":37,"phone":81,"phoneExt":24,"email":82},"Mariella Cataldo","(+39) 080 558 0129","csfliberta@occusol.org",{"facility":84,"status":43,"city":45,"state":45,"zip":85,"country":47,"countryCode":48,"cosmosGeoPoint":86,"geoPoint":88,"contacts":89},"ANAS Puglia (Associazione Nazionale di Azione Sociale)","70125",{"type":50,"coordinates":87},[64,65],{"lat":65,"lon":64},[90],{"name":91,"role":37,"phone":92,"phoneExt":24,"email":93},"Luigi Favia","+39 327 758 6556","anaspromozionesocialepuglia@gmail.com",{"type":95,"investigatorFullName":96,"investigatorTitle":97,"investigatorAffiliation":98,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Elvira Brattico","Professor","University of Aarhus","100575063",false,"NCT06767410","A Multi-domain Intervention for Healthy Aging","A Multi-domain Intervention to Constrast Cognitive Decline in Healthy Aging","MultiMusic","Inclusion Criteria:\n\n* Age ≥ 65\n* Living independently\n\nExclusion Criteria:\n\n* Musical expertise\n* Severe cognitive or functional impairment",true,"ALL","65 Years",{"count":110,"type":111},100,"ESTIMATED","INTERVENTIONAL",[114],"NA","This study aims to investigate the long-term impact of a non-pharmacological intervention including several activities (e.g., physical activity, choir, learning programs, horticulture, etc.) to prevent cognitive impairment in community-dwelling elderly individuals with aspects of frailty. The main questions it aims to answer are:\n\n* Does engaging in multiple activities, including music, slow the degeneration of perceptual and cognitive functions?\n* Is it possible to foster beneficial brain changes even during aging?\n* Can regularly attending social contexts reduce the risk of loneliness and provide fulfillment in later life? Researchers will compare participants involved in the multidomain intervention, including music, to another active group carrying out several activities but without music, and to a passive control group.\n\nParticipants will:\n\n* Participate in the programs for 9 months;\n* Be tested three times (before and after the intervention, and at a 6-month follow-up);\n* Keep a weekly diary of the actual time spent in their activities.",[117],"Healthy Volunteer Study",[119,120,121,122,123],"BDNF","aging","multidomain intervention","music training","neuroplasticity","2025-01-05",{"date":126,"type":127},"2025-01-09","ACTUAL",{"date":129,"type":111},"2025-10-01",{"date":131,"type":111},"2027-12",{"name":5,"class":6},4]