A Prospective, Multicenter, Observational Cohort Study Assessing the Efficacy and Safety of Radiotherapy-sensitized Immunotherapy in Advanced Breast Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

A prospective, multicenter, observational cohort study assessing the efficacy and safety of radiotherapy-sensitized immunotherapy in advanced breast cancer.

Eligibility criteria

Qualifiers

Men or women who are 18 years of age or older on the day of signing the informed consent;

Patients with advanced breast cancer that is inoperable or has metastasized, confirmed by histology or cytology;

Patients who, after MDT discussion at the metastatic breast cancer stage, are considered suitable for radiotherapy and have completed radiotherapy;

Patients who have previously received and continue to use immunotherapy, or are planned to receive immunotherapy, and are scheduled to receive a systemic treatment regimen including immunotherapy as chosen by the physician within 3 weeks after completing radiotherapy;

Disqualifiers

Subjects with brain metastases or leptomeningeal metastases; if there are any suspected symptoms or signs of CNS involvement, they should be excluded by a cranial MRI scan;

Have not signed the informed consent form;

Pregnant or lactating women;

Other conditions deemed unsuitable for inclusion in the study by the investigator.

Trial design

Treatments tested in this trial

  • PD-1 / PD-L1 monoclonal antibody

Treatment groups

No treatment groups listed