[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515280":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":36,"responsibleParty":52,"collaborators":55,"id":59,"slug":12,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":12,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":12,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":12,"overallStatus":39,"whyStopped":12,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Mackay Memorial Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment as Usual (TAU)","NO_INTERVENTION","Treatment-as-usual (TAU) is a naturalistic treatment condition as delivered in current daily practice by psychiatrists in the medical services in Taiwan. TAU typically includes prescription and monitoring of antidepressant and\u002For anxiolytic medication, psychological treatment (this may include empathic listening and\u002For supportive counselling, psychoeducation, etc), or a combination of both. Patients in the TAU condition already receiving any of the aforementioned treatments are informed they will continue to receive as usual the services received before enrollment in the study.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Transdiagnostic Adapted DBT plus TAU","EXPERIMENTAL","The modified DBT protocol, developed by the principal investigator and co-investigators, which will be offered in an individual therapy format. It consists of 15 weekly individual sessions, each lasting 50-60 minutes. It is made based on the manual (Linehan 2015), retaining the essence of DBT (Linehan 1993), and remain dialectically focused. Each session focuses on specific skills within that content of modules.",[18],"Behavioral: Dialectical behavior therapy (DBT)",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","Dialectical behavior therapy (DBT)","The modified DBT protocol, developed by the principal investigator and co-investigators, will be offered in an individual therapy format. It consists of 15 weekly individual sessions, each lasting 50-60 minutes. It is made based on the manual, retaining the essence of DBT and remaining dialectically focused. Each session focuses on specific skills within the context of modules.",[14],[26],{"name":27,"affiliation":5,"role":28},"Shen-Ing Liu, Ph.D","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Hui-Chun Huang, Ph.D","CONTACT","886-2-28094661","3055","aihch@mmh.org.tw",[37],{"facility":38,"status":39,"city":40,"state":12,"zip":12,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"MacKay Memorial Hospital","RECRUITING","Taipei","Taiwan","TW",{"type":44,"coordinates":45},"Point",[46,47],121.52639,25.05306,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":51,"phoneExt":34,"email":35},"886228094661",{"type":28,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Shen-Ing,Liu","Senior Visiting Staff",[56],{"name":57,"class":58},"National Science and Technology Council","FED","100515280",false,"NCT05989451","Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders","Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders in Two Medical Centers: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Mandarin Chinese-language proficiency sufficient to complete the study questionnaire\n2. A current diagnosis of depressive or anxiety disorder as diagnosed from a SCAN interview\n\nExclusion Criteria:\n\n1. Intellectual disability\n2. Substance use disorder in the past three months\n3. Bipolar disorder\n4. Psychotic disorder\n5. Organic brain disorder\n6. Acute suicidality or a history of frequent or recent suicide attempts\n7. Recent (past six weeks) change in psychiatric medication or unwillingness to maintain a stable dosage of medication during study participation\n8. Had received five or more sessions of CBT in the past five years or was unwilling to stop concurrent psychotherapy for an emotional disorder\n9. Any mental or physical condition requiring hospital admission\n10. Another medical condition likely to prevent participation in the study\n\nAs we also aim for a naturalistic setting, we do not exclude patients who undergo a medication change during the trial if this is judged necessary or clinically important by the treating clinician. Instead, we include a question about this in the questionnaire to the referring\u002Ftreating clinician.","ALL","18 Years","65 Years",{"count":69,"type":70},250,"ESTIMATED","INTERVENTIONAL",[73],"NA","Anxiety and depressive disorders, referred to as emotional disorders, have high rates of prevalence, recurrence, and functional impairment. Transdiagnostic psychotherapy targeting shared features of these disorders has recently emerged. Dialectical behavior therapy (DBT) for the transdiagnostic treatment of emotional disorders is a promising approach, as results of preliminary studies for use in a broad range of mental disorders are encouraging. Since there is a lack of research on transdiagnostic psychotherapy in Taiwan, the investigators thus propose this 3-year randomized controlled trial to test the efficacy of a modified DBT for the treatment of transdiagnostic emotional disorders and to further evaluate whether the efficacy of modified DBT differs in the specific emotional disorders. The investigators expect that patients with emotional disorders receiving modified DBT are more likely to improve clinical outcomes, functioning, and quality of life.",[76,77],"Anxiety Disorder","Depressive Disorder","2026-05-27",{"date":80,"type":81},"2026-05-29","ACTUAL",{"date":83,"type":81},"2023-09-01",{"date":85,"type":70},"2026-10",{"name":5,"class":6},1]