Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 2
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorYale University
About this trial
This study is stage 2, round 2 of a larger study which refines and optimizes the EMBED clinical decision support (CDS); see NCT03658642 to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with opioid use disorder.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Emergency department patient
18 years of age or older
Moderate to severe opioid use disorder
Disqualifiers
Under 18 years of age
Pregnant
Currently receiving medication for opioid use disorder
Trial design
Design model
Sequential
Treatments tested in this trial
Refined EMBED CDS
Other interventionRefined EMBED CDS
Provider alert to order consultation with addiction counselor
Other interventionProvider alert to order consult with addiction counselor
Treatment groups
300 Participants
are divided into 2 treatment groupsGroup A: Active Comparator: Refined EMBED CDSActive comparator 1 intervention
Group B: Refined EMBED plus provider alert in Epic to order a consult with an addiction counselorExperimental treatment 2 interventions
Trial outcomes
Primary outcomes
1
Proportion of encounters with an order for an addiction counselor consult
Proportion of encounters with documentation of a clinician order for an addiction counselor consult specifically to assess for eligibility and initiation of MOUD.
Time frame
Trial round start to end up to 3 monthsSecondary outcomes
1
Proportion of encounters with Buprenorphine initiation in the ED
Proportion of eligible encounters with buprenorphine administered in the Emergency Department (ED) and/or prescribed buprenorphine on discharge from the ED. Obtained from EHR data.
Time frame
Trial round start to end up to 3 months2
Proportion of eligible encounters with CDS engagement
Proportion of eligible encounters in which any portion of the EMBED workflow was documented or completed.
Time frame
Trial round start to end up to 3 months3
Proportion of encounters in which buprenorphine was ordered through EMBED vs. externally.
Proportion of eligible encounters in which buprenorphine order is placed through EMBED (i.e., using EMBED order set)
Time frame
Trial round start to end up to 3 months4
Teamwork on ED initiation of buprenorphine
Proportion of encounters with multi-team-member use of EMBED for buprenorphine initiation, out of encounters with any team member use of EMBED for buprenorphine initiation
Time frame
Trial round start to end up to 3 monthsSponsors and contacts
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Yale University
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: