[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622070":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":50,"collaborators":18,"id":52,"slug":18,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":18,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":18,"enrollmentInfo":59,"targetDuration":18,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":18,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"University of Minnesota","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Alternate Nostril Breathing","ACTIVE_COMPARATOR","Participants in the intervention group will receive a brief orientation via a research team member at the time of randomization on alternate nostril breathing (ANB) and then be provided with a written and video-based instructional guide. They will be instructed to perform ANB 3 times per day for 5-10 minutes per session over a 7-day period and document their sessions in a daily symptom diary. The 7-day period will begin the following day after enrollment to allow for a full day of intervention implementation (Day 1-7).",[13],"Behavioral: Alternate Nostril Breathing",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care Only","NO_INTERVENTION","This group will receive usual care and complete a daily symptom diary for Day 1-7.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","ANB 3 times per day for 5-10 minutes per session over a 7-day period",[9],[25],{"name":26,"affiliation":5,"role":27},"Shilpa Babbar","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Erin Wesley","CONTACT","612-624-9208","obgynresearch@umn.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-93.26384,44.97997,{"lat":46,"lon":45},[49],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},{"type":51,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100622070",false,"NCT07378839","Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting","Inclusion Criteria:\n\n* Pregnant individuals aged 18 years or older\n* Viable pregnancy with a gestational age between 6 0\u002F7 - 12 6\u002F7 weeks of gestation, confirmed by last menstrual period or ultrasound\n* Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12)\n* Ability to understand and read English\n\nExclusion Criteria:\n\n* Severe nausea and vomiting, defined as a PUQE score \\>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy\n* Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD)\n* History of severe anxiety disorders affecting breathing patterns\n* Known deviated nasal septum\n* Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy","FEMALE","18 Years",{"count":60,"type":61},100,"ESTIMATED","INTERVENTIONAL",[64],"NA","This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.",[67,68],"Pregnancy Emesis","Nausea","2026-03-16",{"date":71,"type":72},"2026-03-19","ACTUAL",{"date":74,"type":72},"2026-02-10",{"date":76,"type":61},"2027-03-31",{"name":5,"class":6},1]