About this trial
This study aims to evaluate the utility of Analgesia Nociception Index (ANI) monitoring as a predictive and preventive tool for TCR during septoplasty. By comparing standard anesthetic monitoring with ANI-guided analgesia, this research seeks to determine whether maintaining optimal autonomic balance can reduce the incidence of trigeminal cardiac reflex (TCR) and improve intraoperative cardiovascular stability.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-60 years.
American society of anesthesiologist physical status I-II
Indicated for primary septoplasty.
Disqualifiers
Known cardiac arrhythmias or conduction disorders.
Use of beta-blockers or antiarrhythmic medications.
Previous nasal surgery and Combined nasal procedures.
Inability to obtain reliable Analgesia Nociception Index readings.
Trial population
Adult patients scheduled for elective nasal septoplasty under general anesthesia will be enrolled.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Primary Outcome - Incidence of trigeminal cardiac reflex
Defined as a decrease in heart rate \>20% from baseline during surgery.
Secondary outcomes
Time interval between Analgesia Nociception Index drop and subsequent heart rate decrease (early warning window).
Time in minutes between occurrence of Analgesia Nociception Index drop and subsequent heart rate decrease
Total intraoperative opioid consumption.
The amount in milligram of opioid consumption.
Incidence of hypotension or arrhythmias.
Decrease mean arterial pressure less than 60mmgh or occurrence of tachycardia or bradycardia.
Sponsors and contacts
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