[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626620":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":51,"collaborators":25,"id":53,"slug":25,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":25,"enrollmentInfo":62,"targetDuration":25,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":33,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Casa di Cura Dott. Pederzoli","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"combined exercise","EXPERIMENTAL","participants will undergo a combined endurance and resistance exercise training",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","ACTIVE_COMPARATOR","participants performs outcome measures sessions only, including blood sample collection.",[19],"Other: control",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Exercise","All participants will be involved in the exercise training three times per week for 24 weeks: endurance exercise training, resistant exercise training",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"control","outcome measures",[15],[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ospedale P. Pederzoli Casa di Cura Privata S.p.A.","RECRUITING","Peschiera del Garda","Verona","37019","Italy","IT",{"type":40,"coordinates":41},"Point",[42,43],10.68614,45.43912,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":49,"phoneExt":25,"email":50},"Yuri Battaglia, MD","CONTACT","+39 0456444193","urc@ospedalepederzoli.it",{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100626620",false,"NCT07438002","Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment","Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial","TONE","Inclusion Criteria:\n\n* Signature of the informed consent\n* Patients with CKD stage 1 to 5 under conservative treatment\n* Patients undergoing chronic hemodialysis for at least 3 months\n* Age ≥ 18\n\nExclusion Criteria:\n\n* Severe cardiovascular disease (NYHA class IV or hypertension class III)\n* TIA or myocardial ischemia within the last three months\n* Anatomical limitations\n* Health conditions detected during the stress test (CPET)","ALL","18 Years",{"count":63,"type":64},50,"ESTIMATED","INTERVENTIONAL",[67],"NA","This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group",[70],"Chronic Kidney Disease",[72,73,74],"Nephrology","exercise","physical activity","2026-02-20",{"date":77,"type":78},"2026-02-27","ACTUAL",{"date":80,"type":78},"2025-09-02",{"date":82,"type":64},"2026-09",{"name":5,"class":6},1]