Health Trials

Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial

ConditionsNMIBCTURBTBladder (Urothelial, Transitional Cell) CancerBladder Cancer RecurrenceAnesthesia, GeneralAnesthesia,Spinal
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-80
SponsorNational Taiwan University Hospital

About this trial

To demonstrate the superior efficacy of spinal anesthesia (SA) versus general anesthesia (GA) according to the delay of time to recurrence in high-risk NMIBC patients up to Week 104 after TURBT.

Eligibility criteria

Qualifiers

Age ≥40 years for male subjects or postmenopausal female subjects

ECOG performance status 0-2

Patients with suspected or newly diagnosed UBUC

ASA I or II

Disqualifiers

Patients with prior or concurrent UC involving the renal pelvis, ureter or urethra

Patients with clinical evidence of MIBC or mUC

Immunocompromised or immunosuppressed patients

Patients with chronic use of anti-inflammatory agents or beta-blockers

Trial design

Treatments tested in this trial

  • Spinal Anesthesia
  • General Anesthesia

Treatment groups

370 Participants
are divided into 2 treatment groups

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

Department of Urology, College of Medicine, National Taiwan University Status unavailable 100, Taipei, TaipeiTaiwanTaiwan

Sponsors and collaborators

National Taiwan University Hospital

Lead sponsor

Source ClinicalTrials.gov