[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528574":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":27,"responsibleParty":47,"collaborators":10,"id":51,"slug":10,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":52,"sex":56,"minAge":10,"maxAge":57,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"ARREST NEPHROSIS Participants",null,[12],"Other: Registry",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Registry","Registry Participation, providing data and clinical specimen",[9],[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Christoph Aufricht, Prof. MD","CONTACT","+4314040021115","christoph.aufricht@meduniwien.ac.at",{"name":25,"role":21,"phone":22,"phoneExt":10,"email":26},"Lisa Daniel-Fischer, MD","lisa.daniel-fischer@meduniwien.ac.at",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Division of Pediatric Nephrology and Gastroenterology, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090 Vienna, Austria.","RECRUITING","Vienna","1090","Austria","AT",{"type":36,"coordinates":37},"Point",[38,39],16.37208,48.20849,{"lat":39,"lon":38},[42,44,45],{"name":43,"role":21,"phone":22,"phoneExt":10,"email":23},"Christoph Aufricht, Prof MD",{"name":25,"role":21,"phone":22,"phoneExt":10,"email":26},{"name":20,"role":46,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Christoph Aufricht","Prof. Dr.","100528574",false,"NCT06162546","ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and Biobank","Inclusion Criteria:\n\n* Resistant to standard Immunosuppressive agents (if clinically indicated, e.g. primary\u002Fnon-genetic forms)\n* Persistent urinary protein-to-creatinine (UP\u002FC) ratio \\>1.0 g\u002Fg\n* eGFR \\> 30 ml\u002Fmin per 1.73 m2\n* biopsy or a disease-causing genetic mutation associated with nephrotic syndrome\n\nExclusion Criteria:\n\n* Inability or unwillingness to comply with repeated assessments\n* Objections against participation at discretion of the investigator\n* Secondary\n* Patients with steroid-dependence\u002Ffrequently relapsing disease (but achievement of complete remission)","ALL","75 Years",{"count":59,"type":60},100,"ESTIMATED","10 Years","OBSERVATIONAL","Nephrotic syndrome is the clinical phenotype of a heterogeneous group of glomerular diseases that may present with varying degrees of urinary protein loss (proteinuria), dysproteinemia in the blood, fluid retention and impaired renal function.\n\nThe AustRian RESistanT NEPHROtic Syndrome Treatment Response RegIStry and Biobank (ARREST-NEPHROSIS) sets out to achieve the following goals, as typical categories of rare disease registries\n\n1. Obtaining real world data on practice patterns and outcomes\n2. Networking between affected patients, families, and clinicians.\n3. Establish a patient base for facilitated recruitment in studies of drugs, medical devices, and products\n4. Development of a Biobank to enable research of potential biomarkers and therapy or disease courses",[65,66,67,68],"Focal Segmental Glomerulosclerosis","Proteinuria","Nephrotic Syndrome","Nephrotic Syndrome Steroid-Resistant","2023-11-30",{"date":71,"type":72},"2023-12-08","ACTUAL",{"date":74,"type":72},"2023-01-01",{"date":76,"type":60},"2033-12-31",{"name":49,"class":6},1]