[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629752":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":46,"collaborators":49,"id":52,"slug":18,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":18,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SCREEN Arm","ACTIVE_COMPARATOR","SCREEN Arm: 3 rounds of LDCT screening performed at the baseline (T0), 18 ± 3 months (T1), 42 ± 3 months (T2) from baseline",[13],"Diagnostic Test: Low-dose computed tomography (LDCT)",{"label":15,"type":16,"description":17,"interventionNames":18},"CONTROL arm","NO_INTERVENTION","CONTROL arm: No LDCT screening",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","Low-dose computed tomography (LDCT)","3 rounds of LDCT screening performed at the baseline (T0), 18 ± 3 months (T1), 42 ± 3 months (T2) from baseline",[9],[26],{"name":27,"affiliation":28,"role":29},"Dennis KM Ip, MD","School of Public Health, The University of Hong Kong","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Teresa HC So","CONTACT","(+852) 39176714","haso9150@hku.hk",[37],{"facility":28,"status":18,"city":38,"state":18,"zip":18,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":18},"Hong Kong","HK",{"type":41,"coordinates":42},"Point",[43,44],114.17469,22.27832,{"lat":44,"lon":43},{"type":29,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Prof Dennis Kai-Ming Ip","Clinical Associate Professor",[50],{"name":51,"class":6},"The Hong Kong Jockey Club Charities Trust","100629752",false,"NCT07478757","Assessing the Effectiveness of Low-Dose Computed Tomography in Lung Cancer Screening for High-Risk Smokers: A Randomized Controlled Trial in Hong Kong","Inclusion Criteria:\n\n1. Adults aged between 50 and 79 years\n2. Current smokers or ex-smokers quitted for less than 10 years, with a history of cigarette smoking equivalent to at least 20 pack-years\n\nExclusion Criteria:\n\n1. Non-Chinese population\n2. Individuals who are not mentally competent to provide informed consent (e.g., those with a history of dementia)\n3. Individuals with a known prior diagnosis of lung cancer or detection of lung nodules\n4. Individuals with a history of other cancers within the last five years or currently under treatment\n5. Individuals who have undergone a CT scan of the thorax in the previous 12 months\n6. Individuals who are either unwilling to undergo a chest LDCT scan, or having a condition that prevents them from having a LDCT scan (for example, pregnancy or inability to lie flat on the CT table)",true,"ALL","50 Years","79 Years",{"count":62,"type":63},15000,"ESTIMATED","INTERVENTIONAL",[66],"NA","The investigators propose a randomized controlled trial to evaluate the clinical effectiveness of low-dose computed tomography (LDCT) for lung cancer screening in high-risk Chinese ever-smokers aged 50-79 years in Hong Kong and to assess the cost-effectiveness of implementing LDCT for lung cancer screening in the local setting.",[69,70],"Lung Cancer","Lung Cancer Screening",[69,22,72,73],"Screening","High-risk smokers","NOT_YET_RECRUITING","2026-03-12",{"date":77,"type":78},"2026-03-17","ACTUAL",{"date":80,"type":63},"2026-07-01",{"date":82,"type":63},"2037-06-30",{"name":5,"class":6},1]