[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522123":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":36,"centralContacts":40,"locations":45,"responsibleParty":62,"collaborators":64,"id":67,"slug":35,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":35,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":35,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":93,"overallStatus":97,"whyStopped":35,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cancer Survivors","EXPERIMENTAL","Participants will attend a single 15-30 minute study session during which they will answer questionnaires (5-10 minutes) and undergo laryngopharyngeal sensory testing (10-20 minutes). There will be up to 2 years of medical record follow up after completing the main study.",[13,14,15],"Device: Cheung-Bearelly Aesthesiometer","Procedure: Transnasal Laryngoscopy","Other: Questionnaires",[17,24,31],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"DEVICE","Cheung-Bearelly Aesthesiometer","The Cheung-Bearelly Aesthesiometer will be used to deliver a range of calibrated stimuli through the channeled flexible laryngoscope to assess sensation of the laryngopharynx.",[9],[23],"Aesthesiometer",{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"PROCEDURE","Transnasal Laryngoscopy","A procedure to examine your larynx (voice box)",[9],[30],"Transnasal Flexible Laryngoscopy",{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Questionnaires","Patient-reported health and behavioral outcomes measures will be administered",[9],null,[37],{"name":38,"affiliation":5,"role":39},"Yue Ma, MD","PRINCIPAL_INVESTIGATOR",[41],{"name":38,"role":42,"phone":43,"phoneExt":35,"email":44},"CONTACT","877-827-3222","cancertrials@ucsf.edu",[46],{"facility":5,"status":35,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"San Francisco","California","94143","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-122.41942,37.77493,{"lat":56,"lon":55},[59,61],{"name":60,"role":42,"phone":43,"phoneExt":35,"email":44},"Yue Ma",{"name":38,"role":39,"phone":35,"phoneExt":35,"email":35},{"type":63,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR",[65],{"name":66,"class":6},"National Spasmodic Dysphonia Association","100522123",false,"NCT06078527","Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort","Assessment of Laryngopharyngeal Sensation in Patients With Laryngopharyngeal Disorders","Inclusion Criteria:\n\n1. Age \\\u003C=18 years.\n2. Individuals without a laryngopharyngeal disorder (health controls) or with a laryngopharyngeal disorder. Laryngopharyngeal disorder includes but is not limited to: presbylarynx, aspiration; spasmodic dysphonia; globus pharynges; vocal fold paralysis; iatrogenic injury to the larynx; muscle tension dysphonia; neurogenic dysphagia; laryngeal sensory neuropathy; and laryngopharyngeal disorders resulting from prior radiation therapy in individuals with a history of head and neck cancer who have completed radiation therapy as primary or adjuvant cancer treatment\n3. Ability and willingness to comply with study procedures.\n4. Ability to understand a written informed consent document, and the willingness to sign it.\n\nExclusion Criteria:\n\n1. Non-English speaking.\n2. Laryngopharyngeal structures are not accessible on exam.\n3. Known contraindication to any study-related procedure, or history of being unable to tolerate laryngoscopy.\n4. Vocal fold immobility or severe hypomobility on adduction.\n5. For head and neck cancer survivors only: Currently undergoing radiation therapy for head and neck cancer (i.e., primary\u002Fadjuvant radiation therapy treatment plan is not yet completed).","ALL","18 Years","85 Years",{"count":77,"type":78},40,"ESTIMATED","INTERVENTIONAL",[81],"NA","A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders. This study will expand on the previous research to include a separate cohort of adults being seen in clinic for an existing laryngopharyngeal disorder resulting from previous radiation or other cancer treatments.",[84,85,86,87,88,89,90,91,92],"Presbylarynx","Aspiration","Spasmodic Dysphonia","Globus Pharyngeus","Larynx Paralysis","Laryngeal Disease","Vocal Cord Paralysis","Iatrogenic Injury","Sensory Neuropathy",[94,95,96],"Cancer survivors","Previous cancer treatment","Laryngopharyngeal disorders","NOT_YET_RECRUITING","2025-07-21",{"date":100,"type":101},"2025-07-23","ACTUAL",{"date":103,"type":78},"2025-10-01",{"date":105,"type":78},"2028-01-31",{"name":5,"class":6},1]