[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633664":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":15,"responsibleParty":54,"collaborators":56,"id":61,"slug":10,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":73,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"High Stress Cohort",null,"Pancreatic cancer patients who receive radical resection and exhibit high psychological stress (e.g., defined by a specific cut-off score on the evaluation scale).",{"label":13,"type":10,"description":14,"interventionNames":10},"Low Stress Cohort","Pancreatic cancer patients who receive radical resection and exhibit low or normal psychological stress",[16,29,45],{"facility":17,"status":18,"city":19,"state":20,"zip":10,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":10},"the Third Xiangya Hospital of Central South University","NOT_YET_RECRUITING","Changsha","Hunan","China","CN",{"type":24,"coordinates":25},"Point",[26,27],112.97087,28.19874,{"lat":27,"lon":26},{"facility":30,"status":31,"city":32,"state":33,"zip":10,"country":21,"countryCode":22,"cosmosGeoPoint":34,"geoPoint":38,"contacts":39},"Zhongshan Hospital Affiliated to Fudan University","RECRUITING","Shanghai","Shanghai Municipality",{"type":24,"coordinates":35},[36,37],121.45806,31.22222,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Liang Liu","CONTACT","18017317395","liu.liang@zs-hospital.sh.cn",{"facility":46,"status":18,"city":47,"state":48,"zip":10,"country":21,"countryCode":22,"cosmosGeoPoint":49,"geoPoint":53,"contacts":10},"The First Affiliated Hospital of Xi'an Jiao Tong University","Xi’an","Shanxi",{"type":24,"coordinates":50},[51,52],113.52486,35.99785,{"lat":52,"lon":51},{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[57,59],{"name":58,"class":6},"First Affiliated Hospital Xi'an Jiaotong University",{"name":60,"class":6},"The Third Xiangya Hospital of Central South University","100633664",false,"NCT07529626","Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer","A Prospective Cohort Study on the Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer: A Comprehensive Analysis Based on Multidimensional Dynamic Psychological Assessment (MIND-PANC)","MIND-PANC","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Histologically or cytologically confirmed diagnosis of pancreatic cancer, or other pancreatic diseases.\n* Conscious, with basic reading\u002Fwriting or communication skills, able to understand and complete the questionnaire assessments (either independently, with assistance from research staff, or with help from a family member).\n* Voluntarily agree to participate in this study and sign a written informed consent form.\n\nExclusion Criteria:\n\n* Presence of severe cognitive impairment (e.g., dementia, disturbance of consciousness) or a definite history of psychiatric disorders, judged by the investigator as unable to comply with the study assessments, and without a family member who can help complete the questionnaire assessments.\n* Presence of other severe, uncontrolled systemic diseases (e.g., severe heart, lung, or kidney failure), with an estimated life expectancy \\\u003C 3 months as judged by the investigator.\n* Inability to understand Chinese or presence of severe visual\u002Fhearing impairment that affects completion of the questionnaire assessments, and without a family member who can help complete the questionnaire assessments.","ALL","18 Years",{"count":71,"type":72},320,"ESTIMATED","3 Years","OBSERVATIONAL","This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.\n\nResearchers will ask participants to fill out simple questionnaires about their mood, worries, and sleep at the start of the study and at regular follow-up visits. The study will also collect a small blood sample (leftover from routine care) to measure stress-related markers.\n\nInvestigators hypothesize that pancreatic cancer patients who have higher levels of ongoing psychological stress (such as anxiety, depression, or poor sleep) tend to have shorter survival times, a higher chance of recurrence, and a poorer response to treatment, compared to patients with lower stress levels.",[77,78,79],"Pancreatic Tumor, Benign","Pancreatic Cancer, Adult","Pancreatic Cancer Resectable",[81,82,83,84,85,86,87,88,89],"pancreatic cancer","anxiety","depression","psychological distress","Hospital Anxiety and Depression Scale","Pittsburgh Sleep Quality Index","disease progression","Overall survival","quality of life","2026-06-24",{"date":92,"type":93},"2026-06-29","ACTUAL",{"date":95,"type":93},"2026-05-11",{"date":97,"type":72},"2028-12-31",{"name":5,"class":6},3]