This is a prospective, single-arm, open-lable, single-center study and we aimed to determine whether atorvastatin combined with N-acetyl-L-cysteine (NAC) plus romiplostim could induce sustained response off-treatment (SRoT) in adult patients with ITP following CS failure.
Diagnosed with primary ITP;
Aged ≥18 years;
Patients with treatment failure or relapse after first-line corticosteriod therapy for ITP;
Platelet count <30×10⁹/L.
Pregnant or lactating women, and who were possibly pregnant, planning to become pregnant, or who had partners planning to become pregnant;
Presence of active malignant tumors;
Active HBV, HCV or HIV infection;
Active infection requiring systematic treatment;