[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493572":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":30,"centralContacts":34,"locations":41,"responsibleParty":59,"collaborators":39,"id":61,"slug":39,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":39,"enrollmentInfo":70,"targetDuration":39,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":39,"overallStatus":43,"whyStopped":39,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Monthly injection","EXPERIMENTAL","The patients will recive 12 intravitreal injections in one eye and 12 sham injections in the other eye each month",[13],"Procedure: Intravitreal injection of CB-PRP",{"label":15,"type":10,"description":16,"interventionNames":17},"Bimonthly injection","The patients will receive 6 intravitreal injections in one eye and 6 sham injections in the other eye each two months",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Quarterly injection","The patients will receive 4 intravitreal injections in one eye and 4 sham injections in the other eye each three months",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","Intravitreal injection of CB-PRP","The procedure consists in a trans-scleral puncture to access the vitreous cavity, with subsequent injection of CB-PRP",[15,9,19],[29],"CB-PRP",[31],{"name":32,"affiliation":5,"role":33},"Maria Cristina savastano","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":39,"email":40},"Maria Cristina Savastano","CONTACT","+390630155701",null,"mariacristina.savastano@policlinicogemelli.it",[42],{"facility":5,"status":43,"city":44,"state":39,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Rome","00168","Italy","IT",{"type":49,"coordinates":50},"Point",[51,52],12.51133,41.89193,{"lat":52,"lon":51},[55,58],{"name":36,"role":37,"phone":56,"phoneExt":39,"email":57},"+39 3384443002","mariacristina.savastano@unicatt.it",{"name":36,"role":33,"phone":39,"phoneExt":39,"email":39},{"type":60,"investigatorFullName":39,"investigatorTitle":39,"investigatorAffiliation":39,"oldNameTitle":39,"oldOrganization":39},"SPONSOR","100493572",false,"NCT05706896","Atrophic Age-related Macular Degeneration Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma","Atrophic Age-related Macular Degeneration (AMD) Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP): a Pilot Study","CORD-IV","Inclusion Criteria:\n\n* Age ≥65 years\n* Bilateral dry-AMD\n* ETDRS-corrected visual acuity between (or equal to) 1\u002F10 and 4\u002F10\n* No concomitant ocular pathology (e.g., Glaucoma, amblyopia) or systemic pathology that would result in a BIAS for primary goal assessment\n* Signature of informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C 65 years\n* Pregnancy\n* Previous inflammatory\u002Finfectious events involving the eyes\n* Eye trauma, diabetes, or disease potentially damaging to the visual system, even in the absence of impairment at the time of intake\n* Previous intravitreal treatments.\n* Refusal to sign informed consent.","ALL","65 Years",{"count":71,"type":72},36,"ESTIMATED","INTERVENTIONAL",[75],"NA","The objective of the study will be to evaluate the efficacy of intravitreal injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP) in order to reduce or stabilize the atrophic progression in dry Age-related Macular Degeneration (AMD)",[78],"Dry Age-related Macular Degeneration","2025-09-18",{"date":81,"type":82},"2025-09-23","ACTUAL",{"date":84,"type":82},"2022-12-14",{"date":86,"type":72},"2026-02-10",{"name":5,"class":6},1]