Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorOhio State University Comprehensive Cancer Center

About this trial

This randomized clinical trial studies the Beating Lung Cancer in Ohio protocol in improving survival in patients with stage IV non-small cell lung cancer. The Beating Lung Cancer in Ohio protocol may help in evaluating immunotherapies and targeted therapies that prolong survival, have more favorable toxicity profiles than conventional chemotherapy and impact quality of life.

Eligibility criteria

Qualifiers

AIM 1-3

Pathologically confirmed stage IV NSCLC (with any Eastern Cooperative Oncology Group [ECOG] performance status, and any NSCLC - adenocarcinoma, squamous cell, etc.) with available imaging OR patients who do not yet have their staging completed, but in the judgment of the physician are likely to be stage IV;

Patients may be enrolled if the recruiter cannot reach the patient by the first office visit, preferably prior to starting therapy and no later than one month after starting therapy; (NCCN guidelines allow for a switch to targeted therapy from chemotherapy if testing comes back positive after starting chemotherapy)

English speaking; and

Disqualifiers

Being treated with definitive chemoradiotherapy or surgery

Receiving treatment for advanced lung cancer for over one month before enrollment; OR

Trial design

Treatments tested in this trial

  • Best Practice
  • Biospecimen Collection
  • Biospecimen Collection
  • Laboratory Biomarker Analysis
  • Medical Chart Review
  • Quality-of-Life Assessment
  • Questionnaire Administration
  • Smoking Cessation Intervention

Treatment groups

3,584 Participants
are divided into 2 treatment groups