[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100488928":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":53,"collaborators":56,"id":63,"slug":18,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":18,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":18,"enrollmentInfo":71,"targetDuration":18,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":18,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BCa Early Screening Group","EXPERIMENTAL","All participants undergo Urinalysis testing every 6 months for 2 years. Based on the RBC count, each participant will go through each of the screening procedures : \\[cystoscopy + Upper tract imaging\\] or \\[urine marker cancer testing with Cxbladder triage + Upper tract imaging\\] or \\[Repeat urinalysis\\]\n\nPatients with suspicious findings on cystoscopy or imaging will get treatment as per standard of care.\n\nTheir outcomes will be compared to a historical control (bladder cancer detected by standard of care using SEER registries).",[13],"Diagnostic Test: Urinalysis",{"label":15,"type":16,"description":17,"interventionNames":18},"Historical Control Group","NO_INTERVENTION","This will include historical control (bladder cancer detected in patients by standard of care) using SEER registries).",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","Urinalysis","Urine analysis (every 6 months for 2 years); Patients with \\\u003C3 red blood cells (RBCs) per high-powered field (HPF) will repeat screening at 6-month intervals for an average of 2 years.\n\nIf RBCs are 3-25 RBSc\u002FHPF- subjects will undergo- \\[cystoscopy + Upper tract imaging\\] or \\[urine marker cancer testing with Cxbladder triage + Upper tract imaging\\].\n\nIf \\>25 RBCs, subjects will get - \\[cystoscopy + Upper tract imaging\\].",[9],[26],{"name":27,"affiliation":5,"role":28},"Yair Lotan, MD","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","214-648-0389","yair.lotan@UTsouthwestern.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Dallas","Texas","75390","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-96.80667,32.78306,{"lat":46,"lon":45},[49,52],{"name":50,"role":31,"phone":51,"phoneExt":18,"email":18},"Sonobia Garrett","214-645-8787",{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":28,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"yair lotan","Professor-Urology",[57,60],{"name":58,"class":59},"Wilson Charitable Foundation Trust","UNKNOWN",{"name":61,"class":62},"Pacific Edge Limited","INDUSTRY","100488928",false,"NCT05646485","Bladder Cancer Screening Trial","Optimal Screening Strategy for Bladder Cancer in at Risk Patients","Inclusion Criteria:\n\n* Age ≥ 50\n* Smoking: ≥15 pack-year smoking history\n* Occupation:≥ 15 years of occupational exposures including: textile worker, painter, dry cleaners\n\nExclusion Criteria:\n\n* Prior history of bladder, kidney, or prostate cancer\n* Prior evaluation of micro or gross hematuria within the last 2 years\n* Do not provide informed consent","ALL","50 Years",{"count":72,"type":73},1000,"ESTIMATED","INTERVENTIONAL",[76],"NA","There is currently no accepted screening strategy for patients at high risk of developing bladder cancer. This study will ask patients to complete a urine test every 6 months for 2 years to help assess if routine screening helps finding bladder cancer at an earlier stage.",[79,80,81,82],"Bladder Cancer","Urothelial Carcinoma","Hematuria","Smoking Cessation","2026-04-27",{"date":85,"type":86},"2026-05-01","ACTUAL",{"date":88,"type":86},"2023-05-05",{"date":90,"type":73},"2028-04",{"name":5,"class":6},1]