About this trial
Through longitudinal analysis of dynamic changes in DMN functional connectivity before and after sensory training intervention, combined with pain behavioral and functional improvement indicators, this study systematically reveals the central neural remodeling patterns in CNLBP and establishes an objective efficacy evaluation system based on multimodal imaging.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 18 and 60 years old;
Current or past low back pain lasting more than three months; ③ No abnormal sensation or reflex abnormalities in the lower limbs; ④ Able to commit to participating in training three times per week for three months.
Disqualifiers
Fractures, dislocations, structural abnormalities, prior surgery, metal implants, or lumbar disc herniation;
Comorbidities such as severe cardiovascular diseases, neurological disorders, osteoporosis, or metabolic diseases; ③ Low back pain caused by visceral diseases;
VAS score (range 1-10) exceeding 8 points;
Pregnant or lactating women; ⑥ Symptoms of nerve root irritation; ⑦ Recent participation in core stability training.
Trial population
All patients were assigned numbers from 1 to 40. Starting at any row and column in a random number table, 40 random numbers were sequentially recorded in correspondence with the patient numbers. The random numbers were then ranked in ascending order, with ranks 1-20 assigned to the experimental group and ranks 21-40 to the control group. All patients continued to receive conventional treatment and comprehensive rehabilitation therapy.
Trial design
Other
Prospective
Treatments tested in this trial
Multimodal Imaging Evaluation
Other interventionFunctional connectivity analysis of brain networks based on functional magnetic resonance imaging (fMRI) technology
Treatment groups
Trial outcomes
Primary outcomes
VAS
The Visual Analogue Scale (VAS) was used to assess the severity of low back pain, with 0 indicating no pain and 10 indicating unbearable severe pain.
JOA
The Japanese Orthopaedic Association (JOA) efficacy assessment criteria for low back disorders were applied to evaluate lumbar function.
Secondary outcomes
MRI
Magnetic resonance imaging was used to assess the effects of treatment on brain networks.
Locations
Sponsors and contacts
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