[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514688":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":56,"collaborators":59,"id":63,"slug":11,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":11,"enrollmentInfo":72,"targetDuration":11,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":11,"overallStatus":41,"whyStopped":11,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Breathing tasks and Brain mapping with stimulation","EXPERIMENTAL",null,[13,14],"Other: Breathing tasks","Device: Brain mapping with stimulation",[16,20],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"Breathing tasks","Breathing tasks include normal breathing through nose or mouth, breathing while resting wakefully, increase and decrease in breathing rate, and breath counting.",[9],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Brain mapping with stimulation","Electrical stimulation will be used to find specific areas of the brain involved in breathing function. Stimulation will be applied using a Nihon Kohden MEE-1000A neural function measuring system with the MS-120BK extension unit for brain stimulation.",[9],[26],{"name":27,"affiliation":5,"role":28},"Nuria L Lecumberri, MD,PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":11,"email":33},"CONTACT","713-500-7785","Nuria.Lacuey@uth.tmc.edu",{"name":35,"role":31,"phone":36,"phoneExt":11,"email":37},"Sandhya Rani, PhD","713-500-7499","M.R.Sandhya.Rani@uth.tmc.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"The University of Texas Health Science Center at Houston","RECRUITING","Houston","Texas","77030","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-95.36327,29.76328,{"lat":51,"lon":50},[54,55],{"name":27,"role":31,"phone":32,"phoneExt":11,"email":33},{"name":35,"role":31,"phone":36,"phoneExt":11,"email":37},{"type":28,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Nuria Lacuey Lecumberri","Assistant Professor",[60],{"name":61,"class":62},"National Institute of Neurological Disorders and Stroke (NINDS)","NIH","100514688",false,"NCT05981755","Breathing Rescue for SUDEP Prevention","Breathing Rescue for SUDEP Prevention (BreatheS)","BreatheS","Inclusion Criteria:\n\n* diagnosis of intractable focal epilepsy\n* admitted to the Epilepsy Monitoring Unit (EMU) at Memorial Hermann-Texas Medical Center for intracranial subdural strips, grids, or depth electrode placement study (invasive video-EEG)\n\nExclusion Criteria:\n\n* respiratory, cardiac or cerebrovascular disease\n* pregnancy\n* prisoners","ALL","18 Years",{"count":73,"type":74},100,"ESTIMATED","INTERVENTIONAL",[77],"NA","The purpose of this study is to precisely delineate human brain networks that modulate respiration and identify specific brain areas and stimulation techniques that can be used to prevent seizure-induced breathing failure.",[80],"Focal Epilepsy","2025-06-13",{"date":83,"type":84},"2025-06-18","ACTUAL",{"date":86,"type":84},"2023-07-31",{"date":88,"type":74},"2028-06-30",{"name":5,"class":6},1]