[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629705":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":60,"collaborators":25,"id":64,"slug":25,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":25,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Nove de Julho","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobic Training","EXPERIMENTAL","Participants will perform supervised aerobic training on a cycle ergometer, 3 times per week for 12 weeks, 40 minutes per session, at perceived exertion 12-13 on Borg scale.",[13],"Behavioral: Aerobic training",{"label":15,"type":6,"description":16,"interventionNames":17},"Usual Care","Participants will maintain their usual clinical care and daily activities without structured exercise intervention.",[18],"Behavioral: Usual Care",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Aerobic training","Aerobic Exercise Training",[9],null,{"type":21,"name":15,"description":15,"armGroupLabels":27,"otherNames":25},[15],[29],{"name":30,"affiliation":5,"role":31},"Raphael M Ritti-Dias, PhD","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":25,"email":36},"CONTACT","+5519999406878","raphaelritti@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":25,"email":40},"Hélcio Kanegusuku, PhD","+55 11 99539-9557","helciokng@gmail.com",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Associação Brasil Parkinson","RECRUITING","São Paulo","04142-092","Brazil","BR",{"type":50,"coordinates":51},"Point",[52,53],-46.63611,-23.5475,{"lat":53,"lon":52},[56],{"name":57,"role":34,"phone":58,"phoneExt":25,"email":59},"Verônica Souza, MD","+55 11 97445-9125","veronica.souza82@yahoo.com.br",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Raphael Mendes Ritti Dias","Professor","100629705",false,"NCT07478146","Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease","Effects of Aerobic Training on Cerebrovascular Function, Cognitive Performance and Gait Parameters in Patients With Parkinson's Disease: A Randomized Controlled Trial","CardioParkinso","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease\n* Hoehn \\& Yahr stages 1-3\n* Stable antiparkinsonian medication for at least 4 weeks\n* Montreal Cognitive Assessment (MoCA) score ≥ 18\n* Ability to walk independently (with or without assistive device)\n* Medical clearance for participation in moderate-intensity exercise\n\nExclusion Criteria:\n\n* Change in medication\n* Contraindication to exercise","ALL","40 Years",{"count":74,"type":75},40,"ESTIMATED","INTERVENTIONAL",[78],"NA","This randomized controlled trial will investigate the effects of a 12-week supervised aerobic training program on cerebrovascular function, peripheral vascular health, cardiovascular autonomic modulation, cognition, non-motor symptoms, sleep, mood, gait biomechanics, quality of life, and body composition in patients with Parkinson's disease (Hoehn \\& Yahr stages 1-3). Participants will be randomly allocated to aerobic training or usual care.",[81],"PARKINSON DISEASE (Disorder)",[83,84,85,86,87,88,89,90],"aerobic training","exercise","rehabilitation","Cerebral blood flow","neurovascular","gait","cardiovascular function","cognition","2026-04-06",{"date":93,"type":94},"2026-04-13","ACTUAL",{"date":96,"type":94},"2026-02-28",{"date":98,"type":75},"2027-12-31",{"name":62,"class":6},1]