Building Cognitive Resilience to Vaccine Misinformation Using AI: Evidence From a Randomised Trial

ConditionHealthy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorLondon School of Hygiene and Tropical Medicine

About this trial

This study aims to understand how parents and caregivers in the United Kingdom engage with information about childhood vaccination (routine vaccines for children and adolescents, excluding tetanus or international travel-related vaccines) and how tailored digital health tools can help address childhood vaccine misinformation.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Parents or primary caregivers of at least one child under 18 years of age in the UK who is able to answer questions about their child's vaccination status;

Those who have basic literacy in English;

Those who have regular access to a digital device and the internet; and

Those who provide informed consent and agree to participate in the trial

Disqualifiers

Those who have a visual/reading disability that could prevent their participation in or completion of the study activities

Trial design

Design model

Parallel

Treatments tested in this trial

  • AI-driven chatbot

    Behavioral

    A tailored AI-driven chatbot designed to counter vaccine misinformation.

  • Social media infographic

    Behavioral

    A UNICEF social media infographic with three "myth vs. fact" statements on vaccination.

Treatment groups

1,000 Participants
are divided into 2 treatment groups
Group A: AI-driven chatbotExperimental treatment 1 intervention
Group B: Social media infographicActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Parental susceptibility to misinformation about childhood vaccination

The primary outcome of this study will assess parental susceptibility to misinformation about childhood vaccination, defined as parents' ability to accurately distinguish between true and false vaccine-related information. This will be measured using ten statements on childhood vaccines, including four true and six false, rumour-related statements. Two of the rumour-related statements correspond to each of the three misinformation tactics introduced by the chatbot and the UNICEF infographic. This measure reflects parents' ability to identify misinformation containing manipulation tactics they were inoculated against and to distinguish true from false information regarding childhood vaccination. Responses will be recorded as "True", "False", or "Don't know". A composite misinformation susceptibility score will be calculated based on the number of correct responses, with higher scores indicating greater ability to identify vaccine misinformation accurately.

Time frame
From enrollment to the endpoint assessment immediately following the intervention during the same survey session (approximately 20-30 minutes)

Secondary outcomes

1

Self-efficacy

Participants' self-efficacy will be evaluated in two domains: (a) confidence in making informed vaccination decisions for their children, measured with a binary response of "Yes" or "No", and (b) confidence in seeking trustworthy information about childhood vaccinations, measured on a four-point scale from "Not at all confident" to "Very confident".

Time frame
From enrollment to the endpoint assessment immediately following the intervention during the same survey session (approximately 20-30 minutes)

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

London School of Hygiene and Tropical Medicine

Lead sponsor

The University of Hong Kong

Collaborator

This trial is not recruiting at the moment. You can still explore other options: