[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619460":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":33,"responsibleParty":49,"collaborators":18,"id":51,"slug":18,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":18,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":18,"overallStatus":71,"whyStopped":18,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Malmö University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Essix splint","EXPERIMENTAL","The treatment (intraorally applied Essix splint) effect on pain and saliva. Each participant will use the Essix appliance and collect saliva together with a clinical examination and saliva collection at the clinic. A questionary will also be completed.",[13],"Device: Essix splint",{"label":15,"type":16,"description":17,"interventionNames":18},"No Essix splint","NO_INTERVENTION","Effect on pain and saliva while not using the splint: collection of saliva together with a clinical examination and saliva collection at the clinic. A questionary will also be completed.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"DEVICE","The treatment effect of an intraorally applied Essix splint compared with periods without splint use. Each participant will use the Essix appliance and have a no-appliance period in randomized order",[9],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Aurelia Ilgunas, Doctor","CONTACT","0406657000","aurelia.ilgunas@mau.se",{"name":31,"role":27,"phone":28,"phoneExt":18,"email":32},"Thomas List, Professor","thomas.list@mau.se",[34],{"facility":35,"status":18,"city":36,"state":18,"zip":18,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Malmö university","Malmö","Sweden","SE",{"type":40,"coordinates":41},"Point",[42,43],13.00073,55.60587,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":28,"phoneExt":18,"email":48},"Department for the orofacial pain and jaw function","osk@mau.se",{"type":50,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100619460",false,"NCT07344909","Burning Mouth Syndrome: Effects of Occlusal Splint Therapy","The Effects of Essix Splint Therapy on Burning Mouth Syndrome. A Prospective N-of-1 Study.","Inclusion Criteria:\n\n* patients with oral mucosal pain from participants in the previous BMS validation study.\n* greater than 30% pain relief during prior use of an Essix appliance.\n* chronic intraoral pain lasting more than 3 months.\n* age between 18 and 80 years.\n\nExclusion Criteria:\n\n* fibromyalgia\n* ongoing dental treatment","FEMALE","18 Years","80 Years",{"count":61,"type":62},12,"ESTIMATED","INTERVENTIONAL",[65],"NA","Burning Mouth Syndrome (BMS) causes chronic oral pain and significantly affects quality of life. Effective treatments are limited and often provide only temporary relief.\n\nThis prospective N-of-1 study evaluates the effect of an intraoral Essix appliance on pain intensity and salivary secretion in patients with BMS.\n\nSaliva samples are collected and analysed for volume and composition.",[68,69,70],"Burning Mouth Syndrome","Orofacial Pain","Mouth Dryness","NOT_YET_RECRUITING","2026-01-08",{"date":74,"type":75},"2026-01-15","ACTUAL",{"date":74,"type":62},{"date":78,"type":62},"2027-11-01",{"name":5,"class":6},1]