[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436680":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":37,"locations":25,"responsibleParty":47,"collaborators":50,"id":56,"slug":25,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":78,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":25},{"fullName":5,"class":6},"Szeged University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pyrophosphate","EXPERIMENTAL","Disodium pyrophosphate",[13],"Dietary Supplement: Pyrophosphate",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Glucose",[19],"Dietary Supplement: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","50 mg\u002Fkg bwt once daily in gelatine capsules.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Glucose in gelatine capsules.",[15],[30,33],{"name":31,"affiliation":5,"role":32},"László Kovács, MD, Ph.D.","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":35,"role":36},"András Váradi, PhD, DSc","Department of Enzymology, Research Centre for Natural Sciences","STUDY_DIRECTOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"László Kovács, MD, PhD","CONTACT","+36309081611","kovacs.laszlo@med.u-szeged.hu",{"name":44,"role":40,"phone":45,"phoneExt":25,"email":46},"Márta Bocskai, MD","+3662341520","bocskai.marta@med.u-szeged.hu",{"type":32,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"László Kovács MD, PhD","Professor",[51,53],{"name":52,"class":6},"Research Centre for Natural Sciences",{"name":54,"class":55},"University of Debrecen Dept. of Rheumatology","UNKNOWN","100436680",false,"NCT04966416","Calcinosis Reduction by Pyrophosphate in SSC","The Effect of Orally Administered Pyrophosphate on Calcinosis Formation in Systematic Sclerosis","Inclusion Criteria:\n\n* to meet ACR\u002F EULAR classification criteria\n\nExclusion Criteria:\n\n* severe upper minfestation of SSC\n* hypo- or hyperthyreoidism\n* QT prolongation on ECG","ALL","18 Years","70 Years",{"count":66,"type":67},60,"ESTIMATED","INTERVENTIONAL",[70],"NA","Calcinosis, i.e. crystal-like nodules are troublesome complication of systemic sclerosis, an autoimmune disease. Pyrophosphate inhibits its formation is laborytory. We would like to test if orally administered pyrophosphate prevents calcinosis formation.",[73,74],"Systemic Sclerosis","Scleroderma",[76,77],"calcinosis","pyrophosphate","NOT_YET_RECRUITING","2023-05-23",{"date":81,"type":82},"2023-05-25","ACTUAL",{"date":84,"type":67},"2023-08-01",{"date":86,"type":67},"2026-06-30",{"name":5,"class":6}]