[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570279":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":28,"responsibleParty":59,"collaborators":10,"id":62,"slug":10,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":85,"overallStatus":87,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"California Institute of Technology","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Behavioral task battery",null,[12],"Behavioral: Behavioral task performance",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"BEHAVIORAL","Behavioral task performance","Measures of performance on behavioral tasks",[9],[20],{"name":21,"affiliation":5,"role":22},"John P O'Doherty, D.Phil","PRINCIPAL_INVESTIGATOR",[24],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","626-395-5981","jdoherty@hss.caltech.edu",[29,47],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"UCLA Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles","Los Angeles","California","90095","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-118.24368,34.05223,{"lat":40,"lon":39},[43],{"name":44,"role":25,"phone":45,"phoneExt":10,"email":46},"Reza Tadayon-nejad, MD PhD","310-206-6389","RTadayonNejad@mednet.ucla.edu",{"facility":48,"status":10,"city":49,"state":32,"zip":50,"country":34,"countryCode":35,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"California Insitute of Technology","Pasadena","91125",{"type":37,"coordinates":52},[53,54],-118.14452,34.14778,{"lat":54,"lon":53},[57],{"name":58,"role":25,"phone":26,"phoneExt":10,"email":27},"John O'Doherty, D Phil",{"type":22,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"John P. O'Doherty, PhD","Fletcher Jones Professor of Decision Neuroscience","100570279",false,"NCT06705179","Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time","Leveraging Computationally Derived Measures of Individual Differences in Learning and Decision-making to Predict Psychiatric Diagnosis, Symptoms and Changes in Symptom Severity Across Time","CABxtime","Inclusion criteria (healthy control participants):\n\n* Age range of 18 to 65.\n* Not currently having a psychiatric diagnosis determined after psychiatric evaluation by Drs. Tadayon-Nejad and Wei (both are board certified psychiatrists).\n* Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.\n* Ability to give informed consent.\n\nExclusion criteria (healthy control participants):\n\n• Prior history and or current diagnosis of neurological disease.\n\nInclusion criteria (patients):\n\n* Age range of 18 to 65.\n* Psychiatric diagnosis of any type of depressive disorders, any type of anxiety disorders or obsessive-compulsive disorder.\n* Primary or comorbid bipolar disorders are allowed but only if not in the acute manic phase.\n* Comorbidity with autism spectrum disorder (ASD) and attention-deficit\u002Fhyperactivity disorder (ADHD) are allowed.\n* Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.\n* Ability to give informed consent.\n\nExclusion criteria (patients):\n\n* Prior history and or current diagnosis of neurological disease.\n* History or current diagnosis of psychotic disorders.\n* Currently active substance use disorder.",true,"ALL","18 Years","65 Years",{"count":74,"type":75},1100,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric symptoms and diagnoses with a longitudinal approach over a 12 month interval. Participants will be healthy participants recruited through Prolific an on-line crowdsourcing service, and psychiatric patients and healthy participants recruited via UCLA Psychiatry Clinics and UCLA's STAND Program",[81,82,83,84],"Behavior","Depressive Disorder","Anxiety Disorders","Obsessive Compulsive Disorder (OCD)",[86,9],"Computational Psychiatry","NOT_YET_RECRUITING","2024-11-21",{"date":90,"type":91},"2024-11-26","ACTUAL",{"date":93,"type":75},"2025-01-01",{"date":95,"type":75},"2029-12-31",{"name":5,"class":6},2]