Cardiac Arrest Pursuit Trial With Unique Registration and Epidemiologic Surveillance

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-79
SponsorSeoul National University Hospital

About this trial

Identification of Causes and Risk Factors for Out-of-Hospital Cardiac Arrest through Development of Prediction Model and Novel Biomarkers

Study Objectives:

1. To identify causes and risk factors of OHCA incidence that are associated with chronic diseases and health behaviors 2. To identify high risk population for OHCA incidence through development of a prediction model 3. To develop novel biomarkers associated with OHCA incidence, survival, and disabilities

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

19 to 79 years old

Out-of-hospital-cardiac arrest providing resuscitation at the site and visiting the emergency department of the participating hospital or transporting from another hospital emergency room (EMS-treated OHCA)

The cardiac arrest event must not have been predicted for 24 hours before the incident

Disqualifiers

People who do not consent to personal information and blood supply for research

Trauma, submersion, poisoning, hanging, suffocation, or other causes of external causes directly contribute to the cardiac arrest

Patients with a terminal condition known to have no further treatment plans due to malignancy, neurological disease, respiratory disease, rheumatic disease, hematologic disease, renal disease or infectious disease. The terminal condition had to be checked by a doctor or recorded in medical records.

"Do not have a resuscitation" card or record issued by a doctor.

Trial population

* Cases will be consecutive adult patients with EMS-treated OHCA and transport to the 14 emergency departments of participating hospitals. * Matched community-based controls (2:1 matching) will be selected from two health screening centers. Controls are those who visit the participating health screening centers for their health screening program.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

5,340 Participants
are grouped into 2 trial groups
Group A: Early cardiac arrest patients
Group B: Matched community-based controls

Trial outcomes

Primary outcomes

1

Number of Participants With Out-of-hospital Cardiac Arrests

Number of participants with out-of-hospital cardiac arrests, from 19 to 79 years old.

Time frame
A total 1,780 cases (200 cases between September 2017 and August 2018, 600 cases between September 2018 and August 2020, 80 cases between September 2020 and December 2020, and 900 cases between January 2021 and December 2023)

Secondary outcomes

Other outcomes

Sponsors and contacts

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Seoul National University Hospital

Lead sponsor

Korean Center for Disease Control and Prevention

Collaborator