Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorThe First Affiliated Hospital of Henan University of Science and Technology

About this trial

The aim of this study is to compare outcomes in Chinese patients with locally advanced resectable esophageal squamous cell cancer who have received either surgery or definitive chemoradiation (CRT) by the randomized, open-label, multicenter trial.

Eligibility criteria

Qualifiers

Chinese

esophageal squamous cell cancer

mid or lower esophageal cancer

tumor is resectable disease

Disqualifiers

who had distant metastasis to solid visceral organs or local invasion into trachea, descending aorta, or recurrent laryngeal nerve.

who had a serious premorbid condition or a poor physical status that compromised a thoracotomy.

Trial design

Treatments tested in this trial

  • CRT
  • surgery

Treatment groups

196 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The First Affiliated Hospital of Henan University of Science and Technology

Lead sponsor

Jiangsu HengRui Medicine Co., Ltd.

Collaborator

Anyang Tumor Hospital

Collaborator

150th Hospital of PLA

Collaborator