Abdominal distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. This symptomatology is frequently observed in various conditions, including small intestinal bacterial overgrowth (SIBO) and abnormal orocecal transit time (OCTT). The utilization of the breath test as a non-invasive diagnostic approach has become widespread in recent years for identifying SIBO and abnormalities in OCTT. In this study, the prevalence of SIBO and OCTT irregularities in individuals presenting with abdominal distention was ascertained through the implementation of the breath test. Furthermore, the correlation between abdominal distention and SIBO/OCTT was analysed to enhance the elucidation of the underlying etiology of abdominal distention. These findings aim to offer valuable insights for refining clinical comprehension and strategies related to the diagnosis and treatment of abdominal distention.
Patients aged 18 to 70 years.
Patients presenting with the primary complaint of abdominal bloating and/or abdominal distension, or those exhibiting abdominal distension with prominence over other symptoms.
Patients who are pregnant or lactating.
Patients have history of gastrointestinal malignancy or gastrointestinal surgery.
Patients manifesting food intolerance or presenting with a confirmed diagnosis or suspicion of lactose intolerance.
Patients with urinary system (chronic kidney disease, etc.), immune system (scleroderma, etc.), nervous system (Parkinson's disease, etc.), mental system (depression, etc.), or other diseases outside the digestive system.
Abdominal distension patients in the outpatient department at Qilu Hospital of Shandong University.
Other
Cross-sectional
Breath test
Diagnostic testThe concentration of methane and hydrogen in the exhaled gas of patients with Abdominal distention is measured by a breath test to determine the presence of SIBO and abnormal OCTT.
Positive rate of SIBO in patients with abdominal distension
Detect the positive rate of SIBO in patients with abdominal distension by breath test
Positive rate of abnormal OCTT in patients with abdominal distension
Detect the positive rate of abnormal OCTT in patients with abdominal distension by breath test
Correlation between clinical features of patients with abdominal distension and SIBO
Analyze the correlation between clinical features of patients with abdominal distension and SIBO
Correlation between clinical features of patients with abdominal distension and OCTT
Analyze the correlation between clinical features of patients with abdominal distension and OCTT
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Shandong University
Lead sponsor
Qilu Hospital of Shandong University (Qingdao)
Collaborator
Jinan Central Hospital
Collaborator
Zaozhuang Municipal Hospital
Collaborator
Weihai Municipal Hospital
Collaborator
Central Hospital of Zibo
Collaborator
Weifang People's Hospital
Collaborator
Dezhou Hospital Qilu Hospital of Shandong University
Collaborator
Binzhou Medical University
Collaborator
Qihe Xian Renmin Hospital
Collaborator
