Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique
ConditionDimethyl Sulfoxide
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorManipal University College Malaysia
About this trial
Dimethyl sulfoxide (DMSO) wet bonding has shown promising results in several in vitro studies. However, there are a lack of clinical trials which prove the advantages of this technique. The aim of the study is to clinically assess the effect of DMSO wet bonding on composite restoration in non carious cervical lesions.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Two similar non carious cervical lesions (NCCLs) on the facial/labial surfaces of premolars.
NCCLs of score 1-3 on the Smith and Knight tooth wear index.
Favorable occlusion and teeth are in normal contact.
Disqualifiers
NCCLs on the lingual surface.
Medically compromised individuals.
Periodontally compromised teeth.
Bruxism and visible wear facets in the posterior dentition.
Trial design
Design model
Factorial
Treatments tested in this trial
Universal single bond adhesive
Other interventionWill be applied and light cured for 20 seconds.
DMSO
Other interventionDMSO application on tooth followed by active application of universal single bond adhesive and light cured for 20 seconds.
Treatment groups
68 Participants
are divided into 2 treatment groupsGroup A: Universal single bond adhesiveActive comparator 1 intervention
Group B: DMSO application before Universal single bond adhesiveExperimental treatment 2 interventions
Trial outcomes
Primary outcomes
1
Fracture of material
Different fracture patterns and retention failures may occur in relation to the type of restoration: cracks, chipping/ delamination, bulk fractures, or incomplete and complete loss of retention. Assessed by Visual examination and short air drying. Criteria set from Clinically excellent/very good(sufficient) (Score 1) to Clinically poor (entirely insufficient)(Score 5)
Time frame
From treatment to 3-6 months follow up2
Marginal adaptation
There are different interfaces between the dental hard tissue, restorative material, and adhesive and/or luting resin/cement layer. Each interface can degrade and potentially alter marginal adaptation. In clinical practice, it is impossible to distinguish failures between the different interfaces. Therefore, only the marginal adaptation as such can be assessed by visual examination and short air drying. Scores given depending upon the quality of restoration from Clinically excellent/very good (sufficient) (Score 1) to Clinically poor (entirely insufficient) (Score 5)
Time frame
From treatment to 3-6 months follow upLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Manipal University College Malaysia
Lead sponsor
Melaka Manipal Medical College
Sponsor institution
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: