This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time.
The study will include adults without diabetes before surgery who undergo pancreatic surgery as part of routine clinical care at Fondazione Policlinico Universitario A. Gemelli IRCCS.
Researchers will study whether participants develop diabetes after surgery and whether this risk changes according to the type of pancreatic resection.
Information from routine clinical care, metabolic tests, imaging, and pancreatic tissue samples collected during surgery may be used for research analyses.
Adult patients (≥18 years)
No diabetes mellitus at baseline
Undergoing partial, near-total, or total pancreatectomy at the study center
Availability of clinical and metabolic data according to study component
Diabetes mellitus at baseline
Age <18 years
Missing key clinical data precluding eligibility assessment or primary outcome evaluation
Refusal or inability to provide informed consent for the prospective component, where applicable
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead sponsor
European Foundation for the Study of Diabetes
Collaborator