[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609905":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":11,"id":49,"slug":11,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":11,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":11,"enrollmentInfo":57,"targetDuration":11,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":11,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University of Minnesota","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-Intensity Focused Ultrasound","EXPERIMENTAL",null,[13],"Device: Low-Intensity Focused Ultrasound (FUS or LIFU)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DEVICE","Low-Intensity Focused Ultrasound (FUS or LIFU)","We will use an established, currently-marketed device to deliver LIFU neuromodulation.",[9],[21],{"name":22,"affiliation":5,"role":23},"Michael Bronstein","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":11,"email":29},"Miriam Freedman","CONTACT","tel:612-625-3330","bronsteinlab@umn.edu",[31],{"facility":5,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-93.26384,44.97997,{"lat":42,"lon":41},[45],{"name":26,"role":27,"phone":46,"phoneExt":11,"email":29},"612-625-3330",{"type":48,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100609905",false,"NCT07220655","Cognition and Ultrasound","Inclusion Criteria:\n\n* 18 years of age or older\n* Speak English (as assessed by their ability to read\u002Fanswer survey questions)\n* May be required to score in the appropriate range on self-report measures\n\nExclusion Criteria:\n\n* They have a neurological disorder which may impact their fMRI scan or cause their reaction to LIFU to differ from that of healthy adults.\n* They take any psychoactive medication.\n* They are unable to undergo fMRI scanning due to a contraindication such as claustrophobia, unremovable piercings, pregnancy, the presence of medical devices such as pacemakers, or a movement or sleep disorder.\n* Are pregnant, or may have reason to believe that they are pregnant.\n* They have a diagnosis of a psychiatric condition other than depression or anxiety",true,"ALL","18 Years",{"count":58,"type":59},100,"ESTIMATED","INTERVENTIONAL",[62],"NA","Our primary goal is to investigate the role of Low-Intensity Focused Ultrasound (LIFU) neuromodulation on deep brain targets, and its potential to improve cognition",[65],"Healthy Participants","2026-06-12",{"date":68,"type":69},"2026-06-15","ACTUAL",{"date":71,"type":69},"2024-06-01",{"date":73,"type":59},"2028-07-01",{"name":5,"class":6},1]