[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576153":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":42,"responsibleParty":60,"collaborators":25,"id":62,"slug":25,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Hôpital le Vinatier","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Light therapy","ACTIVE_COMPARATOR","Active light therapy comes in the form of glasses and emits an intensity of 1200 Lux and a cyan-colored light spectrum (500nm), corresponding to a retinal exposure of 361.91uW\u002Fcm2 with a 30-min daily exposure upon waking for 2 weeks",[13],"Device: Light therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Light therapy","PLACEBO_COMPARATOR","Sham light therapy is the same device but in an attenuated version (addition of a filter and reduction of light intensity), emitting an intensity of 33 Lux and a light spectrum (600 nm) with a 30-min daily exposure upon waking for 2 weeks.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Light therapy","The intervention consists of 30 minutes of daily exposure to light therapy glasses (active or sham according to randomization) on waking for 2 weeks. The light therapy will be delivered in the patient's home at the same time as CPAP is introduced.",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Sébastien S CATOIRE, DR","Centre Hospitalier le Vinatier","PRINCIPAL_INVESTIGATOR",[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Sébastien S CATOIRE, Dr","CONTACT","+330437915495","+33","sebastien.catoire@ch-le-vinatier.fr",{"name":39,"role":34,"phone":40,"phoneExt":36,"email":41},"Lydie L SARTELET, Mrs","+33(0)437915531","lydie.sartelet@ch-le-vinatier.fr",[43,55],{"facility":29,"status":44,"city":45,"state":46,"zip":47,"country":46,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":25},"RECRUITING","Bron","France","69678","FR",{"type":50,"coordinates":51},"Point",[52,53],4.91303,45.73865,{"lat":53,"lon":52},{"facility":29,"status":56,"city":45,"state":25,"zip":47,"country":46,"countryCode":48,"cosmosGeoPoint":57,"geoPoint":59,"contacts":25},"NOT_YET_RECRUITING",{"type":50,"coordinates":58},[52,53],{"lat":53,"lon":52},{"type":61,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100576153",false,"NCT06781593","Combining Light Therapy and CPAP in Depression","Effects of Light Therapy on Compliance With Continuous Positive Airway Pressure in a Population of Depressed Patients Newly Fitted With Devices for Obstructive Sleep Apnea","LUCIOPRESS","Inclusion Criteria:\n\n* Adults consulting at the MICHEL JOUVET unit, CH Le Vinatier, Bron\n* Adults with a diagnosis of major depressive episode (DSM-V) and with a MADRS score ≥ 15\n* Adults with a diagnosis of OSAS on ventilatory polygraphy or polysomnography (AASM 2017 criteria) requiring CPAP.\n\nExclusion Criteria:\n\n* Refusal to participate.\n* Pregnant and breast-feeding women\n* Under guardianship or curatorship.\n* Unstable psychiatric or physical pathology (e.g., hypomania, high suicidal risk) considered incompatible with the study by the investigators.\n* Other psychiatric, neurologic or somatic conditions\n* Contraindication to light therapy: retinopathy, retinitis pigmentosa, diabetic retinopathy, macular degeneration, glaucoma, recent eye surgery (less than 3 months).\n\npatient wishing to choose a provider other than the protocol provider.\n\n* Patient wishing to choose a device other than SEFAM's S-BOX or a mask other than the nasal mask at the time of introduction.\n* Nasal obstruction.\n* Refusal to use actimetry, refusal to use light therapy, refusal to use CPAP.","ALL","18 Years",{"count":72,"type":73},130,"ESTIMATED","INTERVENTIONAL",[76],"NA","In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.",[79,80,81,82,83,84],"Major Depression","Sleep Architecture","Obstructive Sleep Apnea","Compliance","Continuous Positive Airway Pressure (CPAP)","Light Therapy","2025-04-24",{"date":87,"type":88},"2025-04-29","ACTUAL",{"date":90,"type":88},"2025-01-17",{"date":92,"type":73},"2027-10-30",{"name":5,"class":6},2]