[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100475365":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":25,"id":56,"slug":25,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Western Galilee Hospital-Nahariya","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"women with term prolonged>18h rupture of membrane","ACTIVE_COMPARATOR","women with term prolonged \\>18 h prom or in preterm delivery will be treated with IV ampicillin 2 gr every 6 hours until delivery",[13,14],"Drug: Ampicillin Only Product","Drug: ampicillin plus gentamicin",{"label":16,"type":10,"description":17,"interventionNames":18},"women with preterm labor","women with term prolonged \\>18 h prom or in preterm delivery will be treated with IV ampicillin 2 gr every 6 hours until delivery plus IV gentamicin 5 mg\u002Fkg every 24 hours",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Ampicillin Only Product","women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin",[16,9],null,{"type":21,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"ampicillin plus gentamicin",[16,9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Maya Wolf, MD","CONTACT","972-50-7887800","mayaw@gmc.gov.il",[36],{"facility":37,"status":38,"city":39,"state":25,"zip":25,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Galil Medical Center","RECRUITING","Nahariya","Israel","IL",{"type":43,"coordinates":44},"Point",[45,46],35.09814,33.00892,{"lat":46,"lon":45},[49],{"name":31,"role":32,"phone":50,"phoneExt":25,"email":51},"972-507887800","homesickid@yahoo.com",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Dr. Maya Wolf","Director- Fetal Maternal Medicine Unit","100475365",false,"NCT05469984","Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor","Comparing Obstetrical Outcomes and Infectious Morbidity Between Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor","Inclusion Criteria: maternal age \\> 18 years singleton pregnancy vertex presentation prolonged \\>18 h prom or preterm delivery\n\n\\-\n\nExclusion Criteria:\n\n* GBS carrier\n* preterm premature rupture of membrane for conservative treatment\n* intra-uterine fetal death fetal major anomaly\n* drug allergy for the antibiotic in use in this study\n* women receiving antibiotic treatment for other infection such as urinary tract infection",true,"FEMALE","18 Years","48 Years",{"count":67,"type":68},600,"ESTIMATED","INTERVENTIONAL",[71],"NA","This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity",[74,75],"Preterm Labor With Preterm Delivery","Premature Rupture of Membranes Prolonged",[77,78,79,80,81],"prolonged term PROM","pre-term labor","prophylactic antibiotic","peripartum infection","bacterial distribution","2025-08-05",{"date":84,"type":85},"2025-08-06","ACTUAL",{"date":87,"type":85},"2022-11-25",{"date":89,"type":68},"2025-09-26",{"name":5,"class":6},1]