This study aims to compare the clinical outcomes of debridement, antibiotics, and implant retention (DAIR) and implant removal/replacement methods used in the treatment of fracture-related infections, and to determine the infection-free fracture healing rates and the factors affecting treatment success.
internal fixation after fracture
presence of fistula and/or sinus tract or purulent drainage with dehiscence at the incision site
at least 2 positive deep tissue cultures or at least 3 positive soft tissue cultures
early onset of symptoms (6 weeks)
Under 18 years old patients
prosthetic joint infection
only conservative treatment applied
pathological fracture due to primary bone tumor
The study planned to include over 18 years old patients who underwent internal fixation after fracture, had a fistula and/or sinus tract, or purulent drainage with incision dehiscence, at least 2 positive deep tissue cultures or at least 3 positive soft tissue cultures, whose findings started early (6 weeks), and who underwent DAIR or implant removal/replacement due to fracture-related infection.
Case-only
Retrospective
DAIR
Other interventionDAIR: Debridement, antibiotic retention and implant removal
Implant removal/replacement
Other interventionimplant removal/replacement
Fracture healing rates
Infection-free fracture healing rates
Recurrence rate
Infection recurrence rate
Union time
Time to union
Click on the lead sponsor to view all of their trials.
