Comparison of Palatal Wound Healing in Diabetic and Non-diabetic Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversidade Estadual Paulista Júlio de Mesquita Filho
About this trial
This study aims to characterize and compare the closure of open wounds in the palatal mucosa of diabetic and non-diabetic patients, evaluate clinical, patient-centered and immunological parameters as well as wound microbiome composition.
Eligibility criteria
Qualifiers
Patients with at least 18 years, systemically healthy, with good oral hygiene, assessed by plaque index and gingival index less than 25% (Ainamo, Bay, 1975);
Patients with no morphological or pathological conditions on the palatine donor area;
Patients who present indication for extraction and ridge preservation;
The tooth included in the study, as well as, the adjacent teeth do not present loss of periodontal insertion;
Disqualifiers
Patients with systemic problems (cardiovascular, blood dyscrasias, immunodeficiency, and diabetes, among others) that will contraindicate the surgical procedure;
Patients taking medications known to interfere with the wound healing process or that contraindicate the surgical procedure;
Smokers patients;
Pregnant or lactating patients;
Trial design
Treatments tested in this trial
- Palatal Wound
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov