About this trial
This is a randomized, double-blind, placebo-controlled, parallel-group study evaluating the effects of two distinct Qualia NAD⁺ formulations on intracellular NAD⁺ levels in healthy adults aged 35-75 years. Approximately 180 participants will be randomized to one of three study arms: Qualia NAD⁺ version 1, Qualia NAD⁺ version 2, or placebo. Each participant will take two capsules of their assigned product once daily in the morning, with or without food, over a 28-day period. The primary outcome is the change in intracellular NAD⁺ levels, assessed via at-home finger-stick blood collection at baseline and study completion. Secondary endpoints include changes in aging-related symptoms (AMFS scores), health-related quality of life (RAND SF-36), and evaluation of safety and tolerability. All assessments, including electronic questionnaires, are completed remotely without in-person visits.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Parallel
Treatments tested in this trial
Qualia NAD⁺ version 1
Dietary supplementQualia NAD+ version 1 manufactured by Qualia Life Sciences
Qualia NAD⁺ version 2
Dietary supplementQualia NAD+ version 2 manufactured by Qualia Life Sciences
Placebo
Dietary supplementRice Flour
Treatment groups
Trial outcomes
Primary outcomes
Between-group change in intracellular NAD⁺ levels
To assess between-group differences in the change in intracellular NAD⁺ levels from baseline to Week 4 following supplementation with Qualia NAD version 1, Qualia NAD version 2, or placebo.
Secondary outcomes
Aging-Related Symptoms (AMFS scores)
To evaluate within-group and between-group differences in the change in Aging Male/Female Symptom (AMFS) total and sub-scale scores.
RAND SF-36 Scale Scores
To assess within-group and between-group differences in RAND SF-36 domain scores.
Side effect profile as measured by a custom Safety and Tolerability survey
To evaluate side effect profiles using a custom Safety and Tolerability survey.
Within-group differences in the change in intracellular NAD⁺ levels
To assess within-group differences in the change in intracellular NAD⁺ levels
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: