[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100472473":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":35,"responsibleParty":53,"collaborators":55,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Complex ocular infections (COI)",null,"All patients with an COI (endophtalmitis or hospitalized keratitis)",[13],"Diagnostic Test: NGS for endohtalmitis \u002F Multiplex PCR for keratitis",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","NGS for endohtalmitis \u002F Multiplex PCR for keratitis","For endophtalmitis : optimizing culture and NGS will be realized\n\nFor keratitis: Multiplex PCR will be added on ocular samples",[9],[21],"Bundle of intervervention to optimizing diagnosis of ocular complex infections",[23],{"name":24,"affiliation":5,"role":25},"Etienne CANOUI, MD","PRINCIPAL_INVESTIGATOR",[27,31],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","0033158414267","etienne.canoui@aphp.fr",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Marie BENHAMMANI-GODARD","0033158411190","marie.godard@aphp.fr",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Equipe mobile d'infectiologie, Cochin hospital","RECRUITING","Paris","IDF","75014","France","FR",{"type":45,"coordinates":46},"Point",[47,48],2.3488,48.85341,{"lat":48,"lon":47},[51,52],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[56],{"name":57,"class":6},"URC-CIC Paris Descartes Necker Cochin","100472473",false,"NCT05432336","Complex Ocular Infection, Optimization of Microbiological Diagnosis","ICODIA","Inclusion Criteria:\n\n* Adult patient\n* Patient presenting or having presented a clinical suspicion of complex ocular infection requiring a sample for microbiological diagnosis:\n\n  * Corneal abscess requiring hospitalization\n  * Any suspicion of endogenous or exogenous endophthalmitis.\n* Patient not opposed to participating in the research\n\nExclusion Criteria:\n\n* Patient under guardianship or curatorship\n* Pregnant women","ALL","18 Years",{"count":67,"type":68},153,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to evaluate the impact of different technique to optimize the microbiological diagnosis of the COI.\n\n* Metagenomic for the endophtalmitis\n* Multiplex polymerase chain reaction for corneal abscesses",[72,73],"Endophthalmitis","Keratitis",[75,76,77,78,79],"Endogenous Endophtalmitis","exogenous endophtalmitis","keratitis","PCR","NGS","2025-09-08",{"date":82,"type":83},"2025-09-15","ACTUAL",{"date":85,"type":83},"2023-11-21",{"date":87,"type":68},"2026-01",{"name":5,"class":6},1]