COMPuter-assisted Self-training to Improve EXecutive Function
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-100
SponsorBispebjerg Hospital
About this trial
This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
A diagnose of stroke, cardiac arrest or Parkinson's disease.
Aged 18 years or older.
Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards
Computer and internet access at home.
Disqualifiers
Informed consent not provided
Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator
Not able to participate according to investigator
Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time)
Trial design
Design model
Parallel
Treatments tested in this trial
Computer-based cognitive rehabilitation (CBCR)
BehavioralCBCR are software-programmes for computers which are clinically developed for rehabilitation of various cognitive functions.
General computer-based cognitive stimulation
BehavioralFor this trial we have developed a webpage for general cognitive stimulation, which is designed to provide general computer-based cognitive stimulation.
Treatment groups
307 Participants
are divided into 2 treatment groupsGroup A: Specific computer-based cognitive rehabilitationExperimental treatment 1 intervention
Group B: General computer-based cognitive stimulationActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
CABPad Working Memory Test
Test of working memory. The higher score the better (theoretically infinite score)
Time frame
After the end of the intervention (8 weeks after baseline)Secondary outcomes
1
CABPad Working Memory Test - 3 months follow-up
Test of working memory. The higher score the better (theoretically infinite score)
Time frame
At follow-up visit 3 months after end of intervention2
Minimum Data Set-Home Care- Instrumental Activities of Daily Living (MDS-HC-IADL)
Questionnaire concerning activities of daily living. 0-3 points on an 8-item scale, the fewer points the better.
Time frame
At follow-up visit 3 months after the end of the intervention3
Trail Making A
Test of processing speed and visual attention. The lower score the better (theoretically infinite score)
Time frame
Directly after the intervention, eight weeks after inclusion4
Trail Making A
Test of processing speed and visual attention. The lower score the better (theoretically infinite score)
Time frame
At follow-up visit 3 months after the end of the interventionSponsors and contacts
Click on the lead sponsor to view all of their trials.
Bispebjerg Hospital
Lead sponsor
Rigshospitalet, Denmark
Collaborator
University of Glasgow
Collaborator
University of Basel
Collaborator
Copenhagen Trial Unit, Center for Clinical Intervention Research
Collaborator
Hjernesagen
Collaborator
Göteborg University
Collaborator
Aalborg University Hospital
Collaborator
Neurorehabilitering - Kbh, City of Copenhagen
Collaborator
Source ClinicalTrials.gov