CONFIRM: Magnetic Resonance Guided Radiation Therapy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBrigham and Women's Hospital

About this trial

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

Eligibility criteria

Qualifiers

Participants must have histologically or cytologically confirmed malignancy requiring radiation

Age 18 years of older

ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)

Ability to understand and the willingness to sign a written informed consent document.

Disqualifiers

History of allergic reactions attributed to gadolinium-based IV contrast

Severe claustrophobia or anxiety

Participants who cannot undergo an MRI

Any other exclusion criteria listed in the specific disease site cohort

Trial design

Treatments tested in this trial

  • Viewray MRIdian® Linac

Treatment groups

70 Participants
are divided into 5 treatment groups

Sponsors and collaborators