Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHospices Civils de Lyon
About this trial
Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients.
CRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure.
Although CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability.
The perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport.
Because PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patient.
Admission within the previous 24 hours, or within 24 hours of the onset of a hemodynamic instability criterion (requirement for vasopressors or fluid resuscitation).
Absence of patient objection.
Disqualifiers
Legal guardianship, curatorship, or judicial protection.
No social security coverage.
Morphological abnormalities preventing CRT and IP measurements.
Trial population
Patients admitted to a University Hospital, either to a medical or surgical intensive care unit.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Microcirculation monitoring
Other interventionMicrocirculation monitoring by Capillary Refill Time (CRT) measurements
Microcirculation monitoring
Other interventionMicrocirculation monitoring by Perfusion Index (PI) measurements
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Perfusion index (PI) threshold associated with abnormal capillary refill time (CRT)
The primary endpoint will be the PI threshold associated with abnormal CRT (\> 3 seconds). CRT is measured in seconds and PI in arbitrary units. These parameters will be measured simultaneously on each patient. Measurements will be performed at the inclusion of each patient.
Time frame
At the inclusionSponsors and contacts
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Source ClinicalTrials.gov