Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
ConditionStroke
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Illinois at Chicago
About this trial
Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged as a promising adjuvant to conventional rehabilitation. This project focuses on the development of a long term gait rehabilitation protocol using brain stimulation to improve walking outcomes in people with stroke. The project will also aim to understand the neural mechanisms that are associated with response to the intervention.
Eligibility criteria
Qualifiers
Age greater than 18 years
First ever monohemispheric stroke > 3 months since onset
Residual hemiparetic gait deficits (e.g. abnormal gait pattern)
Able to walk for 5 minutes at self-paced speed. Handheld assistive device is acceptable.
Disqualifiers
General exclusion criteria
Severe osteoporosis
Contracture-limiting range of motion of lower limb
Score of more than 2 on the Modified Ashworth Scale (indicating increased muscle tone through ankle range of motion)
Trial design
Treatments tested in this trial
- Transcranial direct current stimulation (tDCS)
- Ankle motor training
- High intensity interval speed based treadmill training (HIISTT)
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Illinois at Chicago
Lead sponsor
University of Maryland, College Park
Collaborator
Northwestern University
Collaborator
Source ClinicalTrials.gov