Creatine and Perioperative Brain Health

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-75
SponsorMassachusetts General Hospital

About this trial

The goal of this study is to understand the effects of oral creatine supplementation in the perioperative period. Creatine is commonly used to enhance athletic performance, but it can also have positive effects on the brain. Since surgery can lead to alterations in thinking, memory, and attention patterns in some patients, we will assess whether creatine can be protective against these changes in older adults undergoing surgery.

Eligibility criteria

Qualifiers

Patients scheduled for elective surgery under general anesthesia

Disqualifiers

History of creatine deficiency disorders

Severe neurologic or psychiatric diseases

History of stroke or head trauma

Obesity (BMI ≥ 30 kg.m-²), kidney or liver disease

Trial design

Treatments tested in this trial

  • Creatine monohydrate

Treatment groups

80 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators