Cryoablation vs Thoracoscopic Surgery for GGN
ConditionGround-Glass Opacity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Chest Hospital
About this trial
The aim of this study is to investigate the efficacy and safety of Cryoablation and Thoracoscopic Surgery in the treatment of pulmonary ground-glass nodules.
Eligibility criteria
Qualifiers
Patients ≥ 18 years old.
The size of the GGN is 8-20mm (with less than 25% solid component), and the number of nodules requiring treatment in the short term is less than 3.
Pathological confirmation of the GGN as non-small cell lung cancer; or progression of the GGN during at least 3 months of follow-up, including enlargement of the largest diameter, increase in solid component, or the appearance of a significant solid component in a previously pure GGN, with multidisciplinary discussion (including radiology, thoracic surgery, and pulmonology) suggesting malignancy.
No lymph node, pulmonary, or distant metastasis to other organs.
Disqualifiers
Patients in poor general condition, with ECOG physical fitness score >2, unable to tolerate surgery or ablation therapy, or with relevant contraindications.
Patients who have previously received other treatments for pulmonary GGNs.
Patients with poor compliance.
Severe heart, lung, kidney, brain, or other vital organ diseases.
Trial design
Treatments tested in this trial
- Cryoablation
- Thoracoscopic Surgery
Treatment groups
160 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov