[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542231":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":55,"collaborators":18,"id":57,"slug":18,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":18,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":80,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Fluid administration","EXPERIMENTAL","Fluid is given in pleural or subpleural space during CT-guided lung biopsy.",[13],"Procedure: Fluid application during ct-guided lung biopsy",{"label":15,"type":16,"description":17,"interventionNames":18},"No fluid administration","NO_INTERVENTION","No additional fluid is given prior to the CT-guided lung biopsy.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Fluid application during ct-guided lung biopsy","Injection of a small amount of fluid (max. 20 ml sodium chlorid) in the pleural cavity at the biopsy site",[9],[26],{"name":27,"affiliation":28,"role":29},"Michael Brönnimann, MD","Department of Diagnostic, Interventional and Paediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 10, 3010 Bern, Switzerland;","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","+41316326510","michael.broennimann@insel.ch",{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},"Johannes Heverhagen, Prof","+41316322648","johannes.heverhagen@insel.ch",[40],{"facility":41,"status":42,"city":43,"state":18,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 10","RECRUITING","Bern","3010","Switzerland","CH",{"type":48,"coordinates":49},"Point",[50,51],7.44744,46.94809,{"lat":51,"lon":50},[54],{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},{"type":56,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100542231",false,"NCT06340178","CT-guided Lung Biopsy Risk Optimization Method","CT-guided Lung Biopsy Risk Optimization Method - Effect of Fluid Application in the Pleural Cavity and the Gravitational Effect of Pleural Pressure","BROM-I","Inclusion Criteria:\n\n* Ability to provide informed consent (knowledge of project languages), \\>18 years.\n* Indeterminate or suspicious lung lesion unsuitable for transbronchial biopsy or Status after unsuccessful transbronchial biopsy\n* Indication for biopsy given by referring specialist (in patients).\n\nExclusion Criteria:\n\n* Preintervention bleeding into the pleural cavity\n* More than 1 lesion should be biopsied at the same time\n* Infiltration of the thoracic wall\n* Pregnancy",true,"ALL","18 Years","100 Years",{"count":69,"type":70},198,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient positioning to allow biopsy in gravity-dependent areas of the lung.",[76,77,78,79],"Pneumothorax","Biopsy, Needle","Risk Factors","Radiology, Interventional",[81,78,82,83,76],"Image-Guided Biopsy","Tomography","Biopsy","2026-01-29",{"date":86,"type":87},"2026-02-02","ACTUAL",{"date":89,"type":87},"2025-09-29",{"date":91,"type":70},"2027-04-01",{"name":5,"class":6},1]