[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621504":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":31,"locations":36,"responsibleParty":47,"collaborators":25,"id":51,"slug":25,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":25,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":25,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":75,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Hanoi Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Connective Tissue Graft (CTG)","ACTIVE_COMPARATOR","Peri-implant soft tissue augmentation using autogenous connective tissue graft.",[13],"Procedure: Connective Tissue Graft",{"label":15,"type":16,"description":17,"interventionNames":18},"Collagen Matrix","EXPERIMENTAL","Peri-implant soft tissue augmentation using a collagen matrix.",[19],"Device: Collagen Matrix",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","A porcine-derived collagen matrix is used for peri-implant soft tissue augmentation at the time of implant surgery, serving as a substitute for autogenous connective tissue grafting.",[15],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"PROCEDURE","Connective Tissue Graft","An autogenous connective tissue graft harvested from the patient is used for peri-implant soft tissue augmentation at the time of implant surgery.",[9],[32],{"name":33,"role":34,"phone":25,"phoneExt":25,"email":35},"Phu Manh Nguyen, DDS, MSc","CONTACT","manhphu@hmu.edu.vn",[37],{"facility":5,"status":25,"city":38,"state":25,"zip":25,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":25},"Hanoi","Vietnam","VN",{"type":42,"coordinates":43},"Point",[44,45],105.84117,21.0245,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","DUC NGUYEN MINH","DDS","100621504",false,"NCT07371481","CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation","Results of Soft Tissue Grafting Around Implant in the Mandible Molar Area","Inclusion Criteria:\n\nAdults aged 18 to 65 years.\n\nPatients requiring dental implant treatment in the mandibular molar region.\n\nPresence of insufficient peri-implant soft tissue thickness (\\\u003C 2 mm).\n\nAdequate general health to undergo minor oral surgery.\n\nAbility and willingness to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\nSystemic conditions or medications that may impair wound healing.\n\nHeavy smoking (more than 10 cigarettes per day).\n\nHistory of allergy or hypersensitivity to collagen-based materials.\n\nPrevious graft failure or complications at the intended implant site.\n\nLoss of three or more adjacent teeth in the study area (excluding third molars).","ALL","18 Years","65 Years",{"count":61,"type":62},46,"ESTIMATED","INTERVENTIONAL",[65],"NA","This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix. Adult patients requiring implant treatment with insufficient peri-implant soft tissue thickness will be randomly assigned to receive either CTG or a collagen matrix at the time of implant surgery.\n\nThe study aims to evaluate and compare changes in peri-implant soft tissue thickness, width of keratinized tissue, and soft tissue contour over a 9-month follow-up period, as well as the occurrence of postoperative complications. The results of this study will help determine whether a collagen matrix can provide clinical outcomes comparable to those of connective tissue grafting for peri-implant soft tissue augmentation.",[68,69],"Peri-implant Soft Tissue Deficiency","Insufficient Peri-implant Keratinized Tissue",[71,72,73,74],"Peri-implant soft tissue augmentation","Connective tissue graft","Collagen matrix","Dental implant","NOT_YET_RECRUITING","2026-01-27",{"date":78,"type":79},"2026-01-29","ACTUAL",{"date":81,"type":62},"2026-02",{"date":83,"type":62},"2028-12",{"name":5,"class":6},1]