About this trial
Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions.
Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite progress in this field, much remains to be done in clinical, therapeutic and fundamental research to address the efficacy, resistance and side-effects of treatment.
These similarities between IMIDs have led the FHU IMMINeNT to propose the creation of a prospective, multidisciplinary clinical-biological database (IMMINeNT cohort), associated to a biobank, of patients with IMIDs. The main objectives of this database will be to identify new prognostic and therapeutic biomarkers in order to develop new therapeutic targets and biomarkers, to identify prognostic factors and determinants related to the activity, severity and quality of life of patients with IMIDs as well as to the response and tolerance to treatment.
Eligibility criteria
Qualifiers
Patient followed for their IMID in one of the departments of the Lille University Hospital participating in the study (dermatology, internal medicine, neurology, pneumology and rheumatology)
Social insured
Have the capacity to understand the study requirements, provide written informed consent, and comply with the study data collection procedures.
Disqualifiers
Administrative reasons: inability to receive informed information, inability to participate in the entire study, lack of coverage by the social security system.
Pregnant or breastfeeding woman
Persons deprived of liberty
Protected minors or adults
Trial design
Treatments tested in this trial
- Biobanking with genetic analysis
- SF-12 questionnaire
Treatment groups
Sponsors and collaborators
University Hospital, Lille
Lead sponsor
FHU IMMINeNT
Collaborator
FHU PRECISE: Projet Fédératif Hospitalo-Universitaire PREcision health in Complex Immune-mediated inflammatory diseaSEs
Collaborator
Fond de dotation de la Société Française de Dermatologie (SFD)
Collaborator