About this trial
The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual flight simulations, the Precision Instrument Control Task (PICT). The flight simulation test will be conducted at two separate timepoints while the subject is receiving a Functional Magnetic Resonance Imaging (fMRI) scan to evaluate which anatomic and functional brain function is associated with precise performance. By scanning at multiple time points we aim to quantify changes in functional and anatomic connectivity that occur throughout the course of training.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Active Duty Military Pilots (Instructor Pilot Trainees or Remote Piloted Aircraft Trainees)
Age 18-54 years
Biological male or female
Disqualifiers
Age < 18 years
Age > 60 years
Non-active-duty members
History of recurrent migraine headaches requiring chronic suppressive medication or prescription drug intervention more frequently than once per year.
Trial design
Single group
Treatments tested in this trial
fMRI with virtual reality flight simulator
Diagnostic testDuring this scan, the subject will be wearing the stereogenic goggles called the Visual System HD (NordicNeuroLab) mounted in the scanner via a headcoil that can be adjusted to the subject's comfort using the control arm and completely cover the eyes to prevent light exposure and to clearly visualize eye movement during the flight simulation. The subject will be using a visual response system with customized grips to simulate a stick and throttle in a jet cockpit while visualizing the flight simulation (PICT) in the goggles.
Treatment groups
Trial outcomes
Primary outcomes
Flight simulation scores of responses (reaction times and latency)
Assess the flight simulation scores of responses (reaction times and latency) to the anatomical and functional regions of the brain that react when performing corrective flight actions. This will occur by analyzing anatomical MRI and fMRI imaging data and correlate with simulator performance.
Sponsors and contacts
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The Geneva Foundation
Lead sponsor
59th Medical Wing
Collaborator
Uniformed Services University of the Health Sciences
Collaborator