Dextromethorphan for Treatment of Postoperative Pain

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNathanael Heckmann

About this trial

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain

Eligibility criteria

Qualifiers

Patients Age ≥18 planning to undergo total knee arthroplasty

ASA classes I - III

Disqualifiers

BMI ≥ 35

History opioid abuse

History of intractable vomiting after previous surgery

Trial design

Treatments tested in this trial

  • Dextromethorphan Hydrobromide
  • Placebo

Treatment groups

160 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Nathanael Heckmann

Lead sponsor

University of Southern California

Sponsor institution