Diagnosis of Inflammatory Bowel Disease

ConditionInflammatory Bowel Disease (IBD)

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-60

SponsorAssiut University

About this trial

* To quantify the expression of Nuclear enriched abundant transcript 1 (NEAT1) and Anti-sense Non RNA in the INLK4 locus (ANRIL) to determine their potential role as non invasive diagnostic biomarkers in inflammatory bowel disease. * To evaluate the correlation between the studied biomarkers and both the clinical presentation of the patients and the inflammatory mediators like Nuclear factor κB (NF-KB) signaling pathway.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Newly histopathologicaly diagnosed IBD

Disqualifiers

Patients with serious complications as intestinal obstruction, perforation, polyps or colorectal carcinoma

Patients who are taking NSAIDs or Immunosuppressive drugs

Patients who are having other autoimmune disorders

Patients with Chronic infections as TB or other diseases

Trial population

Patients with inflammatory bowel disease

Trial design

Design model

Case-control

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

62 Participants

are grouped into 2 trial groups

Group A: Patients with inflammatory bowel disease

Group B: Healthy normal persons

Trial outcomes

Primary outcomes

To quantify the expression of NEAT1 and ANRIL to determine their potential role as non invasive diagnostic biomarkers in inflammatory bowel disease.

Measure level of NEAT1 and ANRIL genes in blood samples of inflammatory bowel disease patients

Time frame

Baseline

Secondary outcomes

To evaluate the correlation between the studied biomarkers among the studied groups explored and both their clinical presentations and the inflammatory mediators like NF-KB signaling pathway.

To find the relation between the studied biomarkers (NEAT1 and ANRIL) and the inflammatory mediators like NF-KB signaling pathway.

Time frame

Baseline

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: